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Matchday 3 - 27 November 2008
| Group | Home | Away | ||
|---|---|---|---|---|
| A | Schalke | 19:00 | Manchester City | More » |
| A | PSG | 20:45 | Real Racing Club | More » |
| B | Galatasaray | 19:00 | Metalist | More » |
| B | Olympiacos | 20:45 | Benfica | More » |
| C | Sampdoria | 20:45 | Stuttgart | More » |
| C | Partizan | 20:45 | Standard | More » |
| D | NEC | 19:00 | Tottenham | More » |
| D | Dinamo Zagreb | 20:45 | Spartak Moskva | More » |
| E | Portsmouth | 21:05 | Milan | More » |
| E | Braga | 22:30 | Wolfsburg | More » |
| F | Žilina | 18:30 | Slavia | More » |
| F | Hamburg | 21:00 | Ajax | More » |
| G | Club Brugge | 20:45 | St Etienne | More » |
| G | Rosenborg | 20:45 | Valencia | More » |
| H | CSKA Moskva | 18:00 | Lech | More » |
| H | Deportivo | 21:00 | Feyenoord | More » |
