The domestic titles in Slovenia, Croatia and Scotland are likely to be decided this weekend, but there is plenty of jostling for position across the continent. UEFA.com runs the rule over the most eye-catching fixtures.
You can follow the scores throughout the weekend from all the European leagues live on UEFA.com's MatchCentre.
England: Manchester United FC v Tottenham Hotspur FC (Saturday, 12.45)
Ten days ago, United appeared out of the title race while Tottenham's hopes of claiming the final UEFA Champions League spot were dwindling. However, derby wins – two in Spurs' case – proved mutually beneficial and reignited their respective aspirations. Now, with United a point behind leaders Chelsea FC and fourth-placed Tottenham only two ahead of Manchester City FC, victory looks essential for both sides. "It was a big week – I don't think many people would have seen us beating Arsenal and Chelsea," said Tottenham defender Younes Kaboul. "I hope we build on these results this weekend. It will be a very hard game at United but we can get a result. Why not?"
Poland: Wisła Kraków v Lech Poznań (Saturday, 16.00)
Having scored six goals in six games against league leaders Wisła, Lech's 21-year-old Robert Lewandowski will be the player to watch when the Ekstraklasa's top two meet. Expected to move abroad in the summer, the division's 13-goal leading marksman told UEFA.com: "Wisła are still favourites to win the title as they have a four-point lead, but we will push them hard. I like playing Wisła as I score against them quite often. We can expect a great game as both teams love to attack." Wisła defender Arkadiusz Głowacki is suspended while Lech goalkeeper Jasmin Burić is doubtful through injury.
Portugal: SL Benfica v SC Olhanense (Saturday, 21.15)
Liga frontrunners Benfica will look to finish the weekend as Portuguese champions as they play struggling Olhanense at the Estádio da Luz. Six points clear of second-placed SC Braga, Benfica are closing in on their first title since 2005 – and will be celebrating on Sunday provided they better Braga's result away to A. Naval 1º Maio. Although Olhanense held Benfica to a 2-2 draw in the Algarve earlier in the season, the Eagles have oozed class at home, where they have not dropped a point since an opening-day draw. The champagne is on ice.
Spain: RCD Mallorca v Málaga CF (Sunday, 17.00)
Coach Gregorio Manzano has called on Mallorca's fans to "get right behind" the islanders as they seek to consolidate fourth place and a UEFA Champions League ticket against a Málaga side desperate to maintain their Liga status. The Equipo Bermellón have won 14 of their 16 home games this term, compared to just two triumphs on the road, prompting Manzano to label Sunday's encounter "the most important of the season". He warned: "We have Sevilla breathing down our necks and trying to take this golden ticket from us." Opposite number Juan Ramón Muñiz, meanwhile, insisted Málaga – one point above the relegation zone – are "ready to fight".
France: Olympique de Marseille v AS Saint-Étienne (Sunday, 21.00)
With a five-point lead over AJ Auxerre at the top of Ligue 1, Marseille can creep closer to a ninth title, and a first since 1992, when they host record ten-time French champions St-Étienne. Les Verts, still not entirely safe from relegation, have not won a top-flight match at Stade Vélodrome since 1979, yet OM coach Didier Deschamps expects a tough assignment. "I saw their game against Paris Saint-Germain [a 0-0 draw] and they will not be here to make up the numbers," he said. Marseille are pursuing a seventh successive league win ahead of their 2 May trip to Auxerre.
Italy: AS Roma v UC Sampdoria (Sunday, 20.45)
Claudio Ranieri is four games from disproving the Latin maxim 'nemo propheta in patria' (nobody is a prophet in their homeland) by becoming the first Rome-born coach to lead Roma to the Scudetto. However, the Giallorossi face a difficult task as they entertain fourth-placed Sampdoria on Sunday with a single point separating them from FC Internazionale Milano. The Blucerchiati are themselves just two points above US Città di Palermo in the race for the last UEFA Champions League spot. Antonio Cassano should feature against his former club, yet with Roma on a 24-match unbeaten streak, centre-back Juan remains confident: "There are four games left and we know what we have to do: win them all and become champions."
Turkey: Galatasaray AŞ v Bursaspor (Sunday, 19.00)
One point ahead of main rivals Fenerbahçe SK going into the weekend, leaders Bursaspor's wild-card challenge for the Turkish crown faces perhaps its biggest challenge against third-placed Galatasaray, who still have dreams of a title – or at least a UEFA Champions League berth. Fenerbahçe meet Kasımpaşa SK on the same day, but will know to be cautious, having lost 3-1 to the same opponents earlier in the campaign. Bursaspor coach Ertuğrul Sağlam, meanwhile, has rallied the troops, saying: "We have already beaten Beşiktaş and Fenerbahçe at their grounds, and, with a bit of luck, we will do the same against Galatasaray and overcome a big obstacle in our path to the title."
All times are local; England and Portugal are one hour behind CET, Turkey one hour ahead.
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