uefa.com takes its pick of the weekend action as FC Bayern München host BV Borussia Dortmund and high-flying Genoa CFC take on AS Roma. There are also big derby games in north London (click here for preview) and Seville, while the top two meet in Portugal (click here for preview) and AZ Alkmaar are in record-breaking mood.
Germany: FC Bayern München v BV Borussia Dortmund (Sun, 17.00)
This is still one of the most eagerly awaited fixtures in Germany even though Dortmund have fallen on hard times since their last title success in 2002. To make matters worse, they have not won in 16 visits to the Bavarian capital, including a 5-0 defeat in this fixture last season. Only five points separate the sides, though, and Bayern will face a real test as they look to shake off the hangover of last Friday's 1-0 loss at Hamburger SV. "That was a lesson for us," midfielder Martín Demichelis said. "Sunday will be totally different. We will run and fight from the first minute." Leaders TSG 1899 Hoffenheim travel to bottom side VfL Borussia Mönchengladbach on Saturday having had their advantage cut to one point with Hertha BSC Berlin's 1-1 Friday night draw at DSC Arminia Bielefeld.
Italy: Genoa CFC v AS Roma (Sun, 15.00)
Only a year after winning promotion, Genoa's giddy ascent to fourth spot has taken everyone by surprise. Sixth-placed Roma have a real fight on their hands for the fourth UEFA Champions League spot and can ill afford to lose at the Stadio Olimpico on Sunday. "Who would have thought that on Matchday 23 we would be three points above Roma?" said Grifoni coach Gian Piero Gasperini. Unfortunately for him, top scorer Diego Milito is an injury doubt, but a draw would be enough to stay in the top four for another week at least.
France: Olympique de Marseille v FC Girondins de Bordeaux (Sun, 21.00)
Marseille coach Erik Gerets has described Sunday's meeting with Bordeaux as "like a final" as his side look to reverse successive league and cup losses and get back in touch with the top two. Olympique Lyonnais, who are away to OGC Nice, lead the way on 43 points, one more than Bordeaux with OM a further four points behind. Marseille have scored just seven times in their past eleven games prompting Gerets to admit: "We need to find a better understanding between our midfielders and forwards."
Spain: Sevilla FC v Real Betis Balompié (Sat, 22.00)
There may be 16 points and 13 places separating these sides in the Liga but, according to Sevilla midfielder Lautaro Acosta, Saturday night's derby at the Ramón Sánchez Pizjuan "is a game apart". Despite losing their previous two league games to Real Racing Club and Real Sporting de Gijón, Sevilla remain third and can consolidate their position with victory. "No matter what it takes, we have to win," Acosta said. Leaders FC Barcelona host Sporting while Real Madrid CF welcome Racing.
Netherlands: AZ Alkmaar v Willem II (Sat, 19.45)
Eredivisie leaders AZ will be looking for a club record 17th clean sheet this season when they host Willem II on Saturday, which would better the previous best of 16 set in 1974/75 and 2006/07. Goalkeeper Sergio Romero did not let in a goal for the tenth match in succession against Roda JC last Wednesday and has not conceded in 939 minutes, putting him within touching distance of Heinz Stuy's 38-year-old Eredivisie record of 1,082 minutes set during the 1970/71 campaign. Striker Mounir El Hamdaoui, who scored the only goal against Roda, his 17th of the season, said: "Sergio Romero really is excellent. In the first half he made some crucial saves, and with the quality we have up front, you know that one moment always will come."
Turkey: Galatasaray AŞ v Kayserispor (Sat, 19.00)
The Süper Lig's leading scorer Milan Baroš is expected to return after missing Galatasaray's midweek Turkish Cup quarter-final defeat against Sivasspor and coach Michael Skibbe needs all the help he can get with Shabani Nonda, Fernando Meira, Barış Özbek, Aydın Yılmaz, Lincoln and Harry Kewell all injury doubts. Galatasaray have never dropped a point against Kayserispor in Istanbul, but the seventh-placed side boast the best defensive record in the league with just ten goals conceded in 18 games and will be tough to crack. Galatasaray are third on 36 points, two behind joint leaders Trabzonspor, who host MKE Ankaragücü, and Sivasspor who are at home to Kocaelispor.
Greece: Panathinaikos FC v PAOK FC (Sun, 19.00)
Third hosts second in the Greek Super League as PAOK travel to Athens. With leaders Olympiacos CFP eleven points clear of second-placed PAOK the title looks all but decided, but there is prestige at stake, not to mention points in the race for a UEFA Champions League berth. PAOK come into the game with confidence soaring after Sergio Conceiçao's terrific lob proved the winner in Wednesday's Greek Cup quarter-final first-leg win against Olympiacos.
All times local, Greece and Turkey are one hour ahead of CET
Follow the scores live on uefa.com's Matchcentre throughout the weekend.
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