Antonio Di Natale's seventh goal of the season helped Udinese Calcio to a 1-0 win against US Città di Palermo, while S.S. Lazio trail the Bianconeri on goal difference after winning 3-0 at Cagliari Calcio.

The 34-year-old forward found the net seven minutes before the break to maintain his side's impeccable record at the Stadio Friuli and lift them back up to second in Serie A, a point behind leaders Juventus. Lazio remain hot on their heels after first-half goals from Senad Lulić and Miroslav Klose were added to by Tommaso Rocchi late on to secure three points.

ACF Fiorentina condemned Genoa CFC to their first defeat in four, Andrea Lazzari's first-half strike proving the difference, and Parma FC were 2-0 winners against bottom-placed AS Cesena. Goals either side of the interval from Gabriel Paletta and Alessandro Lucarelli consigned Cesena to their sixth reverse this term and promptly led to the sacking of coach Marco Giampaolo, who was appointed this summer.

Two goals from Mattia Destro helped AC Siena triumph 4-1 against AC Chievo Verona, while Bologna FC's revival continued after they recovered from a goal down to win 3-1 at home to Atalanta BC. Elsewhere, US Lecce and Novara Calcio shared the points in a 1-1 draw.