Turkish leaders Fenerbahçe SK take on second-placed Galatasaray AŞ, Olympique de Marseille aim to move closer to the Ligue 1 leaders as they face rivals Paris Saint-Germain FC, while two of Germany's top three also meet this weekend. uefa.com previews the action and you can follow the scores throughout the weekend from all the European leagues live on uefa.com's MatchCentre.
Turkey: Fenerbahçe SK v Galatasaray AŞ (Sunday, 20.00)
Something will have to give in Istanbul as Fenerbahçe – who started the season with a Turkish-record eight straight Süper Lig victories – host second-placed Galatasaray, who themselves have won seven out of nine games. With both sides triumphant in the UEFA Europa League in midweek, the big question is whether Christoph Daum's defensively rigorous Fenerbahçe can contain Frank Rijkaard's ebullient Galatasaray with their buccaneering 4-3-3 formation. Fenerbahçe left-back Roberto Carlos said: "The fans will see a great game between the top two. It's impossible to predict the outcome." Galatasaray striker Shabani Nonda added: "We have a chance to go top if we beat them, our target is three points."
France: Olympique de Marseille v Paris Saint-Germain FC (Sunday, 21.00)
Fresh from getting off the mark in UEFA Champions League Group C with Wednesday's 1-0 victory against FC Zürich, Marseille turn their attentions to staying within touching distance of Ligue 1's stumbling leaders. Olympique Lyonnais and FC Girondins de Bordeaux both lost last weekend to leave Marseille three points off the summit. They sit fifth, four points and as many places higher than arch-rivals PSG – who are without a league win since 30 August – ahead of their meeting at the Stade Vélodrome. "This is a good way to get ourselves back on track," said PSG striker and former Marseille charge Péguy Luyindula. "We would have preferred to go there with more points but this game remains special."
Spain: Real Sporting de Gijón v Real Madrid CF (Saturday, 20.00)
Madrid go to Gijon looking for the boost they received at El Molinón last season when Los Merengues ran out 4-0 winners, not least after climbing to within a point of FC Barcelona a week ago. Things may prove slightly more difficult for Manuel Pellegrini's side on Saturday, however, with seventh-placed Sporting enjoying a rich run of form with only one loss in six games. Madrid, in contrast, have been beaten in two of their last three competitive fixtures. Home coach Manuel Preciado said: "Why should we consider ceding possession to Real Madrid? We'll be doing the opposite and trying to enjoy ourselves as well as competing. They're coming here at a good moment for us."
Germany: FC Schalke 04 v Hamburger SV (Sunday, 17.30)
Having led VfL Wolfsburg to a surprise title last season, Felix Magath switched to Schalke, seeing better long-term prospects, and has already worked wonders. Eighth in 2008/09, Schalke now lie third and could go first if they defeat second-placed Hamburg on Sunday and leaders Bayer 04 Leverkusen lose to BV Borussia Dortmund. Magath, however, warns that "we are not a top team yet." Rather, he believes they are benefiting from opposition mistakes, while accepting that his defence – breached six times in nine league matches – is "top". All optimism is tempered, though: "We don't hold the ball well up front and make too many mistakes there." That opinion is shared by most fans – despite Schalke's ranking so far, they are still not considered serious title challengers. But that went for Wolfsburg last season too.
Italy: ACF Fiorentina v SSC Napoli (Sunday, 15.00)
After a good draw at Juventus last weekend and an important 4-3 UEFA Champions League win at Debreceni VSC, now comes the moment of truth for fourth-placed Fiorentina, who trail pace-setting FC Internazionale Milano by four points in Serie A. Cesare Prandelli's players must prove themselves against Napoli, who won their first game under new coach Walter Mazzarri against Bologna FC last Sunday. The Viola boss has an embarrassment of attacking options, with Alberto Gilardino – scorer of five goals in ten days including two Italy matches and the Debrecen tie – Adrian Mutu and rising star Stevan Jovetić. "Napoli have improved a lot and beat Bologna," said Gilardino. "I always give my all on the pitch and am happy with my form, but it will be a tough game for us."
Belgium: KV Mechelen v RSC Anderlecht (Sunday, 20.00)
Belgian leaders Club Brugge KV visit KSV Roeselare early Sunday evening knowing any slip-up will open the door for second-placed Mechelen and Anderlecht in third. Brugge's nearest rivals trail by one and three points respectively and will both be attempting to stake a claim as the closest challengers for top spot. Mechelen returned to Belgium's élite division in 2007 after a brief hiatus in which they dropped to the third tier, but coach Peter Maes wants more than to tread water ahead of this potentially decisive encounter. "We experience this together as a club," said Maes, an Anderlecht goalkeeper between 1990 and 1995. "We worked hard to get this far, and it feels good. Against Anderlecht we will just keep working the way we have."
Romania: CFR 1907 Cluj v FC Timişoara (Sunday, 20.45)
FC Rapid Bucureşti led Romania's Liga 1 until their 4-1 home defeat by CFR on 17 October, combined with Timişoara's 6-0 thrashing of FC Ceahlaul Piatra Neamt, bumped them down to third – and left the new top two to contest pole position on Sunday. Both arrive on the back of UEFA Europa League action and in the knowledge that third-placed Rapid and fourth-placed FC Steaua Bucureşti, both two points short of the joint leaders, meet prior to kick-off. This term's pacesetters shared the spoils last season, with a 2-1 home triumph for Timişoara and a 2-0 return victory for CFR. António Conceição's hosts have not lost this fixture since promotion in 2004, but will be missing the injured Yssouf Koné and Emil Dică. Timişoara, deprived of Marián Cišovský, will be out to avenge their 3-0 Romanian Cup final defeat in June.
Ukraine: FC Dnipro Dnipropetrovsk v FC Dynamo Kyiv (Saturday, 18.00)
Held 2-2 by FC Shakhtar Donetsk at their Dnipro Arena earlier this month, the third-placed club welcome unbeaten leaders Dynamo with the aim of closing the seven-point gap between the teams. Dynamo won their last five games in Dnipro's old Dnipropetrovsk Stadium; Dnipro captain Andrei Rusol is determined to improve on that statistic in the new. "Against Shakhtar Donetsk we could only draw 2-2," he said. "Against Dynamo, we will try not to repeat our mistakes and finally beat Kyiv."
All times local; Romania, Turkey and Ukraine are one hour ahead of CET. Follow the scores throughout the weekend from all the European leagues live on uefa.com's MatchCentre.
©UEFA.com 1998-2015. All rights reserved.