Chelsea FC 0-1 FC Internazionale Milano (agg: 1-3) José Mourinho enjoyed a happy return to Stamford Bridge as Samuel Eto'o's late goal confirmed the visitors' place in the last eight.
Sevilla FC 1-2 PFC CSKA Moskva (agg: 2-3) Keisuke Honda set up one and scored the winner as the Russian side reached the quarter-finals for the first time.
José Mourinho was in ebullient mood after the defeat of his former employers Chelsea FC took FC Internazionale Milano into the quarter-finals in impressive fashion.
As Manuel Jiménez reflected on missed chances and a "disastrous" defeat for Sevilla FC, PFC CSKA Moskva boss Leonid Slutsky was typically composed despite securing a historic first.
Pep Guardiola will send his FC Barcelona side out to attack even though a goalless draw at home to VfB Stuttgart would book a UEFA Champions League quarter-final place.
Domestic struggles will be put to one side when out-of-sorts Olympiacos FC and FC Girondins de Bordeaux meet in France aiming for a place "among the eight best teams in Europe".
After missing FC Girondins de Bordeaux's 1-0 win at Olympiacos FC three weeks ago, captain Alou Diarra is back and calling on the French champions to reach the quarter-finals.
Jaouad Zairi has spent much of his career in France and hopes for a happy return as Olympiacos FC aim to reverse a 1-0 first-leg defeat against Ligue 1 champions FC Girondins de Bordeaux.
As FC Girondins de Bordeaux prepare to face Olympiacos FC for a quarter-final place, Laurent Blanc says his side have shed the "complex" that once dogged them against Europe's elite.
José Mourinho enjoyed a happy return to Stamford Bridge as Samuel Eto'o's late goal confirmed the visitors' place in the last eight.