Cristiano Ronaldo and Harry Kane both scored twice in wins for Real Madrid and Tottenham respectively, with the more surprising figure of John Stones also at the double for Manchester City.
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- Watch highlights of all Wednesday's games
- Record 54 goals scored on matchday one
- Ronaldo strikes twice in Real Madrid win
- Tottenham beat Dortmund, Man. City hit four
- Matchday two: 26/27 September
Liverpool 2-2 Sevilla
The spoils were shared after a topsy-turvy encounter at Anfield, Liverpool's six-game home European winning streak ended despite the fact they came back to lead after Wissam Ben Yedder had put Sevilla in front after only five minutes.
Maribor 1-1 Spartak Moskva
Maribor looked set for defeat in their first group stage appearance since 2012/13, but Damjan Bohar popped up with five minutes left to earn them a point.
Feyenoord 0-4 Manchester City
The unlikely figure of centre-back John Stones scored twice as Manchester City equalled their biggest ever win in this competition, making it a miserable return to the group stage after 15 years away for Feyenoord.
Shakhtar Donetsk 2-1 Napoli
Arkadiusz Milik's second-half penalty made Shakhtar sweat, but earlier goals from Taison and Facundo Ferreyra were enough for the hosts to prevail.
Porto 1-3 Beşiktaş
Talisca broke the deadlock 13 minutes in – the first goal Porto have conceded this season – with Cenk Tosun's stunner and Ryan Babel's late effort wrapping up the points.
RB Leipzig 1-1 Monaco
Emil Forsberg had the honour of registering Leipzig's first ever UEFA Champions League goal, only for Youri Tielemans to open his Monaco account a minute later.
Real Madrid 3-0 APOEL
Cristiano Ronaldo picked up from where he left off last term, netting his 106th and 107th UEFA Champions League goals as the holders made a winning start to their title defence.
Tottenham Hotspur 3-1 Borussia Dortmund
Harry Kane notched twice as Spurs condemned Dortmund – back at Wembley, where they lost the 2013 final – to a first defeat in 13 matches.
Group A: Manchester United 3-0 Basel, Benfica 1-2 CSKA
Group B: Bayern 3-0 Anderlecht, Celtic 0-5 Paris
Group C: Chelsea 6-0 Qarabağ, Roma 0-0 Atlético
Group D: Barcelona 3-0 Juventus, Olympiacos 2-3 Sporting CP