The 23-year-old French international who only moved to England from AJ Auxerre in the summer, was taken to hospital after several minutes of treatment on the pitch following a first-half fall. Liverpool face a striker shortage for Wednesday's UEFA Champions League trip to RC Deportivo La Coruña, with Florent Sinama-Pongolle also on the casualty list after suffering an ankle injury in midweek.
Liverpool confirmed a fracture of the tibia and fracture of the fibula in Cissé's left leg. The club added: "Djibril will undergo surgery on Sunday morning to insert a pin in the tibia.
Unfortunately he is unlikely to play again this season and everybody at the club wishes him the speediest of recoveries."
Blackburn's Ewood Park is not a happy destination for Liverpool as Milan Baroš and Jamie Carragher both suffered broken legs in the same fixture last season. Baroš fared better this time around, however, scoring a second-half equaliser to give Rafael Benítez's side a 2-2 draw. The Czech international should spearhead the Liverpool attack against Deportivo, with the club's only other fit forward being the inexperienced Neil Mellor.
Cissé's injury will come as a further setback to his international chances after he missed UEFA EURO 2004™ through suspension. He has been involved in qualifying for the 2006 FIFA World Cup but has yet to establish himself as a regular. France's next match is a 17 November friendly against Poland at Stade de France.
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