The English, Spanish and Italian leaders all won away at the weekend ahead of UEFA Champions League dates.
Chelsea FC and FC Barcelona both won on Saturday to extend their domestic leads to eight points - just the tonic each need ahead of the second leg of their UEFA Champions League last-16 tie. uefa.com rounds up the domestic news for teams in European action on Tuesday.
Chelsea FC v FC Barcelona
A 3-1 win at Norwich City FC gave Chelsea an increased advantage at the top of the Premiership thanks to Manchester United FC's draw at Crystal Palace FC. Joe Cole, Mateja Kezman and Ricardo Carvalho were on target for Chelsea, who on Tuesday will be without Wayne Bridge (ankle), Robert Huth (knee) and Scott Parker (broken foot). However, winger Arjen Robben may recover from his own broken foot to play some part against Barça, who won the first leg 2-1. Didier Drogba's red card at Camp Nou rules the striker out of the Stamford Bridge return.
Samuel Eto'o scored the only goal, his 18th in the Primera División this season, as Barcelona triumphed 1-0 at CA Osasuna. Real Madrid CF were held 1-1 by Valencia CF, allowing the Catalan side to pull further clear having slipped slightly in midweek when they were held 0-0 by local rivals RCD Espanyol at Camp Nou. Although both Carles Puyol and Víctor Valdés required medical attention after receiving blows at El Sadar, Barça emerged from the victory with just one injury concern - Rafael Márquez was taken off at half-time with a hamstring pull and will not travel to London. Gabri García, Thiago Motta, Edmílson and Henrik Larsson remain sidelined, however.
AC Milan v Manchester United FC
Milan made it six wins in a row as Andrea Pirlo scored the winning goal in added time against Atalanta BC, a success which enabled the Rossoneri to continue to fend off Juventus FC, themselves 2-1 winners against AS Roma, at the top of Serie A. Massimo Ambrosini opened the scoring for Milan in the 74th minute before Stephen Makinwa equalised for the bottom club a minute later. Coach Carlo Ancelotti was without Andriy Shevchenko and Kakha Kaladze through injury and Rui Costa with flu, although the Portuguese playmaker should be available as Milan defend a 1-0 lead on home turf against United. In a further boost, Filippo Inzaghi played for 15 minutes following a four-month lay off, while Gennaro Gattuso and Clarence Seedorf were rested and Cafu suspended.
Ten-man Crystal Palace FC dented United's English title hopes as they defended bravely to secure a 0-0 draw at Selhurst Park. Louis Saha picked up a knock in training which rules him out of the trip to the San Siro and Gary Neville is also a doubt with an ankle injury sustained at Portsmouth FC on 26 February. Kleberson remains sidelined with a similar complaint and fellow midfielder Darren Fletcher is out with knee ligament problems.
Olympique Lyonnais v Werder Bremen
They may be expected to defend a 3-0 Champions League lead on home soil, but Lyon's form has slipped in the last week. On Tuesday they lost on penalties to Ligue 2 Clermont Foot Auvergne in the French Cup - the champions having even needed a last-gasp Sylvain Wiltord goal to reach extra time with a 1-1 draw - and three nights later the French leaders fell to their second Ligue 1 defeat this season, 1-0 at lowly SM Caen.
Bremen saw their hopes of retaining the Bundesliga title reduced on Saturday as they lost 1-0 at FC Bayern München to fall seven points behind the leaders. They did, however, beat Bayern's amateur side on Tuesday 3-0 to reach the German Cup semi-finals. Ivan Klasnic missed the trip to Munich with a calf injury but should be fit to participate in Lyon.
FC Internazionale Milano v FC Porto
With Milan at home on Tuesday, the home leg of Inter's tie against Porto is being played on 15 March. Despite being without Alvaro Recoba (ankle), Christian Vieri (knee), Emre Belözoglu and Cristiano Zanetti (both flu), Inter coach Roberto Mancini saw his side return to winning ways after last week's Milan derby disappointment by defeating US Lecce 2-1 in Serie A thanks to goals from Iván Cordoba and Adriano. Left-back Giuseppe Favalli sustained a thigh injury and was substituted midway through the first half, his absence leaving the Nerazzurri without any Italian players on the pitch.
Porto, who remain without the injured Boswinga, kept their place at the top of the Portuguese SuperLiga on Saturday as a last-gasp goal from Benni McCarthy wrapped up a 2-1 win at FC Penafiel. Pedro Emanuel's 81st-minute header had cancelled out the home side's surprise opener. The extra week before the second leg could see Porto midfield player Maniche regain full fitness after he felt a recurrence of the hernia injury which kept him out recently and was substituted at half-time.