F91 Dudelange will defend a two-goal aggregate lead on home soil next Tuesday after Jean-Sébastien Legros and Jean-Philippe Caillet struck in the second half of their encounter against the Andorran champions to gain the upper hand in their UEFA Champions League first qualifying round tie.
Although there was little to choose between the two sides during a hard-fought first period, the hosts passed up a presentable opportunity to take the lead when striker and captain Norberto Urbani failed to connect with a deflected shot with only goalkeeper Jonathan Joubert to beat.
When the deadlock was broken 12 minutes after the interval, it was the visitors who stole ahead, as Legros launched himself at a pinpoint right-wing cross by Sofian Benzouien to send a diving header past Ricardo Fernández.
Santa Coloma struggled to contend with Daniel Theis's side thereafter and, eleven minutes from time, Benzouien was again the architect, picking out Caillet at the far post with a wonderful free-kick from the left flank, which the Dudelange defender met with a firm header.
The two sides reconvene on Tuesday 5 July for the right to meet NK Maribor in the second qualifying round on 12/13 July.