After the Bundesliga's three sides earned crucial first-leg results away from home, German hopes of having the largest contingent in the quarter-finals are alive and well. 

| Olympiacos | 1-2 | Schalke | ||
| Referee: David Fernández Borbalán (ESP) – Stadium: Georgios Karaiskakis Stadium, Piraeus (GRE) | ||||
| 12/07/2012 06:39:48 | ||||
| Schalke | 2-2 | Montpellier | ||
| Referee: Sergei Karasev (RUS) – Stadium: Stadion Gelsenkirchen, Gelsenkirchen (GER) | ||||
| 12/07/2012 06:39:48 | ||||
| Arsenal | 0-2 | Schalke | ||
| Referee: Jonas Eriksson (SWE) – Stadium: Arsenal Stadium, London (ENG) | ||||
| 12/07/2012 06:39:48 | ||||
| Schalke | 2-2 | Arsenal | ||
| Referee: Nicola Rizzoli (ITA) – Stadium: Stadion Gelsenkirchen, Gelsenkirchen (GER) | ||||
| 12/07/2012 06:39:49 | ||||
| Schalke | 1-0 | Olympiacos | ||
| Referee: Björn Kuipers (NED) – Stadium: Stadion Gelsenkirchen, Gelsenkirchen (GER) | ||||
| 12/07/2012 06:39:52 | ||||
| Montpellier | 1-1 | Schalke | ||
| Referee: Antonio Mateu Lahoz (ESP) – Stadium: La Mosson, Montpellier (FRA) | ||||
| 01/19/2013 10:35:00 | ||||
| Galatasaray | 1-1 | Schalke | ||
| Referee: William Collum (SCO) – Stadium: Ali Sami Yen Spor Kompleksi, Istanbul (TUR) | ||||
| 02/21/2013 23:07:25 | ||||
| Schalke | 2-3 | Galatasaray | ||
| Aggregate: 3-4 | ||||
| Referee: Jonas Eriksson (SWE) – Stadium: Stadion Gelsenkirchen, Gelsenkirchen (GER) | ||||
| 03/13/2013 23:06:15 | ||||
| P | Pts | ||
|---|---|---|---|
| 1 | 6 | 12 | |
| 2 | 6 | 10 | |
| 3 | 6 | 9 | |
| 4 | 6 | 2 |
Legend:
| Player | Goals | P |
|---|---|---|
| 4 | 7 | |
| 2 | 8 | |
| 1 | 2 | |
| 1 | 4 | |
| 1 | 6 |
| Recent campaigns | |||||
|---|---|---|---|---|---|
| Season | Stage | P | W | D | L |
| 2010/11 | Semi-finals | 12 | 7 | 2 | 3 |
| 2008/09 | Third qualifying round | 2 | 1 | 0 | 1 |
| 2007/08 | Quarter-finals | 10 | 3 | 2 | 5 |
| 2005/06 | Group stage | 6 | 2 | 2 | 2 |
| 2001/02 | Group stage | 6 | 2 | 0 | 4 |
| Full UEFA competition record | ||||
|---|---|---|---|---|
| Competition | P | W | D | L |
| UEFA Champions League | 51 | 21 | 12 | 18 |
| UEFA Cup Winners' Cup | 14 | 9 | 2 | 3 |
| UEFA Europa League | 80 | 40 | 20 | 20 |
| UEFA Intertoto Cup | 12 | 10 | 2 | 0 |