78Deulofeu (in) - Tello (out) (Barcelona)
78Matić (Benfica) is cautioned by the referee.- 74André Almeida (in) - Rodrigo (out) (Benfica)
- 74Óscar Cardozo (in) - Lima (out) (Benfica)
The Paraguayan comes on aiming to add to his record of 10 goals in 23 UEFA Champions League matches - 66Piqué (in) - Adriano (out) (Barcelona)
Another familiar face comes on in the form of Gerard Piqué, who will line-up alongside Carles Puyol at the heart of Barcelona's defence - 63Bruno César (in) - Nolito (out) (Benfica)
- 60Adriano (Barcelona) is cautioned by the referee.
- 59Luisão (Benfica) is cautioned by the referee.
- 58Messi (in) - Rafinha (out) (Barcelona)
The Camp Nou faithful rises to their feet as the Argentine makes his entrace - 56Garay (Benfica) is cautioned by the referee.
- 49Rafinha (Barcelona) is cautioned by the referee.
The referee blows for half-time.
Benfica will be kicking themselves that they were unable to open the scoring after they created five or six openings, but they remain on course for the knock-out stages because Celtic FC are drawing 1-1 with FC Spartak Mosvka- 43Nolito (Benfica) is cautioned by the referee.
Benfica will look back on an evening where they had a host of chances to wrap up the match and reach the knockout stages, for Barcelona though their minds will immediately focus on Lionel Messi's fitness after he was stretchered off late in the second half.