All eyes will be on Cristiano Ronaldo when he returns to Old Trafford with Real Madrid CF for the second leg of their UEFA Champions League round of 16 contest against Manchester United FC.
• Ronaldo spent six years at United and was on target against his old club in the first leg on 13 February, cancelling out Danny Welbeck's 20th-minute opener to earn Madrid a 1-1 draw.
• These clubs have met in four previous European Cup ties with the winners going on to lift the trophy on three occasions. Madrid came out on top in the semi-finals in 1956/57 and quarter-finals in 1999/2000 and also 2002/03 (when they went out in the last four); United prevailed in the 1967/68 semi-finals.
• Madrid overcame United 6-5 on aggregate in a memorable encounter ten seasons ago. Vicente del Bosque's side emerged 3-1 winners from the first leg at the Bernabéu, Luís Figo and Raúl González (2) scoring before Ruud van Nistelrooy pulled a goal back.
• The Brazilian Ronaldo struck a hat-trick in the Old Trafford return, leaving the pitch to applause from the home supporters who then saw United fight back to win 4-3 through two goals from substitute David Beckham. Van Nistelrooy and Iván Helguera (own goal) also found the net.
• The lineups from that Old Trafford meeting on 23 April 2003 were:
Man Utd: Barthez, O'Shea, Ferdinand, Brown, Silvestre (P Neville 79), Verón (Beckham 63), Butt, Keane (Fortune 82), Giggs, Van Nistelrooy, Solskjær.
Madrid: Casillas, Salgado, Hierro, Helguera, Roberto Carlos, Zidane, McManaman (Portillo 69), Figo (Pavón 88), Makelele, Ronaldo (Solari 67), Guti.
• In the 1999/2000 quarter-finals, eventual champions Madrid advanced 3-2 on aggregate as they followed up a goalless home draw by taking a 3-0 lead in Manchester through Roy Keane's own goal and a Raúl double, before Beckham and Paul Scholes replied for the then holders. Ryan Giggs and Iker Casillas also featured.
• George Best got the only goal of the teams' 1967/68 semi-final first leg at Old Trafford. United then battled back from 3-1 behind to draw 3-3 in Madrid and went on to lift the trophy for the first time.
• Madrid won the first-ever meeting 5-3 on aggregate to reach the 1956/57 final. The Merengues overcame Matt Busby's men 3-1 at home and then led 2-0 at half-time in Manchester through goals from Raymond Kopa and Héctor Rial. However, Tommy Taylor and Bobby Charlton then set the tone for a series of United fightbacks in this fixture by making it 2-2.
• United lost 3-2 at home to Athletic Club in last term's UEFA Europa League round of 16 and have won only one of their last five Old Trafford fixtures against Liga visitors – the 1-0 UEFA Champions League semi-final success over FC Barcelona in 2008, courtesy of a Scholes goal. Their overall home record against Spanish opponents is W8 D9 L3.
• Sir Alex Ferguson's side went down 1-0 to CFR 1907 Cluj in their last European home outing, albeit with qualification already secured. They had previously beaten Galatasaray AŞ and SC Braga.
• United have won nine of the 12 UEFA competition ties in which they recorded a first-leg away draw, including three where the score in the first match was 1-1: against Willem II (1963/64 European Cup Winners' Cup preliminary round, 6-0 second leg); AS Saint-Étienne (1977/78 European Cup Winners' Cup first round, 2-0 second leg); and Olympique Lyonnais (2007/08 UEFA Champions League round of 16, 1-0 second leg).
• Under José Mourinho, Madrid have lost just two of 15 away fixtures in the UEFA Champions League. They drew 1-1 at Manchester City FC in the group stage, Karim Benzema scoring their goal. Overall, their record in England is W4 D3 L5.
• Cristiano Ronaldo scored the only goal when Madrid last won in England, 1-0 at Tottenham Hotspur FC in the 2010/11 quarter-finals.
• Madrid have been held at home in the first leg of eight previous UEFA competition ties – all in the European Cup – and have recorded only one aggregate victory, against United in 1999/2000. They have drawn 1-1 at home four times and subsequently been eliminated in every tie, most recently by FC Dynamo Kyiv in the 1998/99 quarter-finals (0-2 away).
• Madrid lost the 1981 European Champion Clubs' Cup final to Liverpool and the 1971 European Cup Winners' Cup final to Chelsea FC.
• United lost UEFA Champions League finals against Barcelona in 2009 and 2011 having beaten the same opponents in the 1991 European Cup Winners' Cup final. Sir Alex oversaw Aberdeen FC's 2-1 defeat of Madrid in the 1983 Cup Winners' Cup final – his first European trophy.
• United's shoot-out record in UEFA club competitions is:
6-5 v Chelsea FC, 2007/08 UEFA Champions League final
3-4 v FC Torpedo Moskva, 1992/93 UEFA Cup first round
4-5 v Videoton FC, 1984/85 UEFA Cup quarter-finals
• Madrid's shoot-out record is:
1-3 v FC Bayern München, 2011/12 UEFA Champions League semi-finals
3-1 v Juventus, 1986/87 European Cup second round
5-6 v FK Crvena zvezda, 1974/75 European Cup Winners' Cup quarter-finals
• Mourinho has faced United twice before at this stage of the UEFA Champions League, starting with FC Porto's success in the 2003/04 round of 16 en route to winning the trophy. A side including Ricardo Carvalho earned a 2-1 advantage at home, securing a 3-2 aggregate win as Costinha cancelled out a Scholes goal with a 90th-minute equaliser.
• Mourinho's FC Internazionale Milano lost to United in the 2008/09 last 16. After a goalless first leg, Inter succumbed 2-0 at Old Trafford, Nemanja Vidić and Ronaldo scoring.
• Mourinho's overall record at Old Trafford is W2 D2 L2. His reign as Chelsea manager started with a 1-0 home victory against Sir Alex's United on 15 August 2004. During three years in London, Mourinho's record against the Red Devils was W5 D4 L1, with the FA Community Shield in August 2007 counting as a draw having finished 1-1 before United prevailed on penalties.
• Mourinho's Chelsea team, including Michael Essien, were 1-0 extra-time winners against United in the 2007 FA Cup final. Rio Ferdinand, Vidić, Darren Fletcher, Michael Carrick, Scholes, Giggs and Wayne Rooney all played for United.
• Ronaldo spent six seasons with United between 2003 and 2009. He scored 118 goals in 292 games, winning one UEFA Champions League and three Premier League titles, as well as one FA Cup and two League Cups.
• Ronaldo played in two UEFA Champions League finals with United. He scored in the 1-1 draw against Carvalho and Essien's Chelsea in Moscow in 2008, where United triumphed on penalties although Ronaldo failed from the spot. Twelve months later, his final United appearance ended in defeat by Barcelona in Rome.
• Essien was in the Olympique Lyonnais side that met United in the 2004/05 group stage, earning a 2-2 home draw before a 2-1 away loss.
• Xabi Alonso had to wait until his fifth and final season with Liverpool, 2008/09, before victory over United – his solitary success in seven attempts. Álvaro Arbeloa lost all three games against United as a Liverpool player.
• Luka Modrić won none of his eight meetings with United while at Tottenham Hotspur FC between 2008 and 2012. In his first campaign he lost the League Cup final on penalties and scored to put Spurs 2-0 up at Old Trafford in a league match they eventually lost 5-2.
• Kaká was in the Milan side that overcame United in the 2004/05 UEFA Champions League round of 16 and, two seasons later, scored three goals – two of them at Old Trafford – as Milan defeated United 5-3 on aggregate in the semi-finals.
• As a Club Atlético de Madrid player, David de Gea conceded 11 goals in five straight derby losses to the Merengues.
• Spain's Casillas, Sergio Ramos and Alonso won the 2010 FIFA World Cup final at the expense of Robin van Persie's Netherlands. The following season Van Persie faced Barcelona with Arsenal FC in the UEFA Champions League round of 16, scoring in a 2-1 first-leg victory but receiving a red card in a 3-1 second-leg defeat.
• Wayne Rooney was in the England side beaten 4-1 by Sami Khedira and Mesut Özil's Germany in the round of 16 of the 2010 World Cup. Khedira and Özil had previously helped Germany win the 2009 UEFA European Under-21 Championship with a 4-0 final triumph over England in which Özil scored.
• Jonny Evans's Northern Ireland frustrated Ronaldo and Pepe's Portugal in a 1-1 2014 World Cup qualifying draw in Porto in October.
• Brazil's Rafael made his senior international debut in a May 2012 friendly against Denmark alongside Marcelo.
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