Centralniy Stadion - Kazan 22/11/2012 - 18:00CET (21:00 local time)
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| 3-0 | |

FC Rubin Kazan held off a concerted fightback from an experimental FC Internazionale Milano side to seal top spot in Group H.
Gökdeniz Karadeniz's early strike set the tone for a dominant first-half performance, but the hosts were forced onto the back foot after the restart, with substitute Rodrigo Palacio hitting the post. Rubin replacement José Rondón did likewise with five minutes left, outmuscling Isaac Donkor on the break and connecting with the woodwork – his effort finished in the net, however, and the Venezuelan forward made it 3-0 in added time.
Rubin | Internazionale | ||
| 1 | Ryzhikov (GK) | 27 | Belec (GK) |
| 2 | Kuzmin | 6 | Silvestre |
| 3 | Ansaldi | 7 | Coutinho |
| 6 | Orbaiz | 21 | Gargano |
| 10 | Kasaev | 23 | Ranocchia (C) |
| 22 | Dyadyun | 24 | Benassi |
| 23 | R. Eremenko | 31 | Álvaro Pereira |
| 27 | Bocchetti | 40 | Juan |
| 61 | Gökdeniz Karadeniz | 42 | Jonathan |
| 66 | Natcho | 52 | Romanò |
| 76 | Sharonov (C) | 88 | Livaja |
Substitutes | |||
| 24 | Arlauskis (GK) | 12 | Castellazzi (GK) |
| 9 | Davydov | 4 | Zanetti |
| 11 | Carlos Eduardo | 8 | Palacio |
| 25 | Marcano | 28 | Pasa |
| 55 | Gökhan Töre | 48 | Bandini |
| 99 | Rondón | 54 | Donkor |
| 61 | Garritano | ||
Coaches | |||
| Kurban Berdyev (RUS) | Andrea Stramaccioni (ITA) | ||
Referee | |||
| Tommy Skjerven (NOR) | |||
| P | Pts | ||
|---|---|---|---|
| 1 | 5 | 13 | |
| 2 | 5 | 10 | |
| 3 | 5 | 2 | |
| 4 | 5 | 2 |
Legend:
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