Fenerbahçe SK will look to make it to the last four of a major UEFA competition for the first time as they take on S.S. Lazio.
• The sides are meeting for the first time.
• Fenerbahçe have played 13 games against Italian sides with the record W3 D0 L10 (W3 D0 L4 at home – W0 D0 L6 in Italy). They have won their last two home games against Italian sides without conceding, but have lost all of their six games in Italy by margins of two goals or more.
• Lazio's record in eight games against Turkish sides is W6 D1 L1 (W3 D1 L0 at home – W3 D0 L1 in Turkey). They have scored twice in all three of their victories in Turkey, where they have won on their last two visits, but have yet to win a home game against a Turkish club by a margin of more than one goal.
• Lazio last reached the quarter-finals of a UEFA competition in 2002/03, when they beat Fenerbahçe's neighbours Beşiktaş JK (1-0 home, 2-1 away) in the UEFA Cup last eight but lost to FC Porto in the next round.
• Lazio coach Vladimir Petković encountered Aykut Kocaman's Fenerbahçe while in charge of Samsunspor, the sides drawing 0-0 in Istanbul in October 2011.
• Petković's BSC Young Boys, featuring Lazio left-back Senad Lulić, eliminated Kocaman's Fenerbahçe from the 2010/11 UEFA Champions League third qualifying round, winning 1-0 in Istanbul after a 2-2 draw in Berne. "As a coach, this is probably my greatest victory ever," Petković said.
• Lazio are the only surviving team who are yet to lose in this season's competition, recording eight wins and four draws from the play-offs onwards.
• Fenerbahçe have now reached the quarter-finals of all three major UEFA club competitions, having played in the last eight of the UEFA Champions League (2007/08) and European Cup Winners' Cup (1963/64). They lost both ties, though it took a replay against MTK Budapest to decide the latter.
• Lazio's biggest success in this competition came when they reached the 1998 UEFA Cup final, losing 3-0 to Serie A rivals FC Internazionale Milano in Paris. They won the final edition of the UEFA Cup Winners' Cup the following season.
• A hat-trick against VfB Stuttgart in the round of 32 second leg moved Lazio's Libor Kozák above SSC Napoli's Edinson Cavani at the top of this season's UEFA Europa League scoring list. The Czech striker has managed eight goals in eight games (and only five starts) since the start of the group stage.
• Lazio are the highest scoring side left in the competition with 19 goals since the start of the group stage, one fewer than eliminated Inter (Chelsea have scored 21 in the same period, but 16 of them came in the UEFA Champions League). Eleven of those strikes have come in the first half, with four more in the first 15 minutes after the break.
• Midfielders Mehmet Topal, Cristian and Caner Erkin are the only players who have featured in all ten of Fenerbahçe's games since the start of the group stage. None of the three have played the full 900 minutes; Mehmet is the only player to have made ten starts.
• Midfielder Hernanes is the only Lazio player to have featured in all ten of their games, making nine starts.
• Lazio's Lorik Cana spent 2010/11 with Galatasaray AŞ before moving to Rome. His side drew 0-0 away and lost 2-1 at home against Fenerbahçe.
• Aykut Kocaman made his name with Fenerbahçe as a striker, winning two titles in an eight-year stint (1988–96). He moved into coaching at Istanbulspor AŞ and – following spells at Malatyaspor, Konyaspor and Ankaraspor AŞ – became Fenerbahçe's director of football. He then took over as coach in 2010, winning the title in his first season and the Turkish Cup in the next campaign.
• Lazio's coach since June, Petković won a Yugoslavian title as a midfielder with hometown club FK Sarajevo in 1984/85 before moving to Switzerland, where he played at a lower level and coached AC Bellinzona, Young Boys and FC Sion, as well as moving to Turkey to take charge of Samsunspor.
• Czech coach Zdeněk Zeman was in charge at Lazio (1994-1997) and Fenerbahçe (1999-2000).
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