Salzburg have taken control of the tie thanks to a 2-1 victory at Borussia Dortmund, who must end the Austrian side's long unbeaten run to stay in the competition.
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Bidding to become the first Austrian club to reach the UEFA Europa League quarter-finals, Salzburg are in charge of this round of 16 tie as they host Borussia Dortmund armed with a 2-1 lead from the first leg in Germany – a result that prolonged their unbeaten run in Europe to 18 matches.
• UEFA Europa League regulars Salzburg won their group for the fourth time – a competition record – before eliminating Real Sociedad 4-3 on aggregate in the round of 32 and thus making a second appearance in the last 16.
• Having crossed over to this competition after finishing third in their UEFA Champions League group with just two points, Dortmund claimed their first European win of the season by defeating Atalanta 3-2 in the home leg of the round of 32 before sealing their passage thanks to substitute Marcel Schmelzer's late equaliser in Italy (1-1).
• Salzburg claimed their first win on German soil in the first leg thanks to two goals early in the second half from Kosovo international midfielder Valon Berisha, the first from the penalty spot. André Schürrle bundled the ball home from close range for Dortmund soon afterwards but the Austrian club held on in the first competitive meeting between the two clubs.
• Salzburg have lost four of their nine matches against German clubs, winning three. The first two victories both came in Austria, most recently against Dortmund's local rivals Schalke on matchday six of last season's UEFA Europa League group stage (2-0), although they were already eliminated.
• Both Eintracht Frankfurt and Karlsruhe were eliminated by Salzburg en route to the 1993/94 UEFA Cup final. Those were landmark triumphs as no Austrian side had ever previously knocked out German opposition from a European competition..
• Before the first leg Dortmund had a flawless record against Austrian clubs in UEFA matches, winning four out of four. Their path to the 2015/16 UEFA Europa League quarter-finals began with a third qualifying round victory over Wolfsberg, a 1-0 away win preceding a 5-0 victory at home in which Marco Reus opened the scoring.
• Salzburg are unbeaten in their last 18 European matches (W11 D7), since a 1-0 defeat at home to Nice on matchday three of last season's UEFA Europa League. That includes a run of eight games without defeat at home (W6 D2), which started with that victory over Schalke and has yielded just two goals to the opposition.
• Having come undefeated through the UEFA Europa League group stage for a record fourth time, this is Salzburg's second appearance in the round of 16. The Austrian club have never gone beyond this round in seven previous UEFA Europa League participations, their only tie at this stage having ended in defeat to Basel in 2013/14 (0-0 away, 1-2 home).
• Salzburg's concession of just one goal in the group stage equalled another UEFA Europa League record, set by Standard Liège in 2011/12, although the seven goals they scored amounted to the lowest number registered by any of this season's 12 group winners.
• Austrian league and cup double winners for the past four seasons, and 1994 UEFA Cup runners-up, Salzburg missed the cut in last year's UEFA Europa League group stage – after succeeding in their previous three attempts.
• Dortmund are without a victory in seven European away matches (D3 L4), the 1-1 draw at Atalanta in the round of 32 ending a run of three successive defeats outside Germany in spring knockout games.
• The German club registered just two points in their autumn UEFA Champions League campaign but managed to take third place in Group H on goal difference ahead of Cypriot club APOEL. It was the first time in 13 group campaigns in that competition that they failed to register a win.
• Dortmund have scored and conceded in all nine of their European fixtures this season.
• The Schwarzgelben reached the quarter-finals in their most recent UEFA Europa League adventure, in 2015/16, having defeated Tottenham 3-0 at home and 2-1 away in the round of 16.
• Dortmund qualified for this season's UEFA Champions League after finishing third in the 2016/17 Bundesliga. They also won the German Cup last term, defeating Eintracht Frankfurt 2-1 in the Berlin final.
• Salzburg have qualified from all nine of the previous European ties in which they have posted an away win in the first leg, two of those having taken place earlier this season when they overcame Maltese side Hibernians in the UEFA Champions League second qualifying round (3-0 away, 3-0 home) and Viitorul of Romania in the UEFA Europa League play-offs (3-1 away, 4-0 home).
• The only previous time they have won the first leg away by a 2-1 scoreline – against Maccabi Haifa in the 1994/95 UEFA Champions League qualifying phase – they also won the return 3-1.
• Dortmund have lost all six of the UEFA competition ties in which they lost the first leg at home, most recently in last season's UEFA Champions League quarter-final against Monaco (2-3 home, 1-3 away). Aside from that tie, all of their other first-leg home defeats have been by a margin of two goals, including the 1992/93 UEFA Cup final which they lost against Juventus (1-3 home, 0-3 away).
Links and trivia
• Dortmund are one of three former UEFA Champions League winners remaining in the UEFA Europa League field, Marseille and Milan being the others.
• Salzburg are the only reigning domestic champions left in the competition. Six others were eliminated in the round of 32 – Astana, Celtic, FC København, Ludogorets, Partizan and Spartak Moskva.
• This is the Austrian club's 16th European match in 2017/18 – more than any other team in the UEFA Europa League round of 16. Defender Andreas Ulmer has been on the field for every minute of a campaign that began in the second qualifying round of the UEFA Champions League, with striker Munas Dabbur also starting all 15 matches.
• Salzburg are bidding to make Austria the 14th nation represented in the UEFA Europa League quarter-finals. No other Austrian club has made it as far as the round of 16.
• Dortmund were one of only three clubs – alongside French duo Lyon and Marseille – to come through their round of 32 tie after playing the first leg at home.
• Salzburg won last season's UEFA Youth League, beating Benfica in the final under Marco Rose – now in charge of the senior side.
• André Schürrle was a Mainz team-mate of Rose between 2009 and 2011.
• Ömer Toprak and André Ramalho played together at Bayer Leverkusen in 2015/16.
• Shinji Kagawa and Takumi Minamino played two games together for Japan in autumn 2015.
• Dortmund's Austrian coach Peter Stöger played against Salzburg for several teams in his homeland, scoring five goals in 42 appearances with the record W18 D9 L15. His coaching record against them with Austria Wien and Wiener Neustadt was W1 D3 L6.
• Stöger was in charge of Köln in this season's UEFA Europa League group stage, leaving before matchday six.
• Dortmund trio Reus, Schürrle and Mario Götze have all scored international goals for Germany against Austria.
• Jérôme Onguéné is currently on loan to Salzburg from German Bundesliga club VfB Stuttgart.
• This season Salzburg became the first club to win their UEFA Europa League group on four occasions. Eleven others have achieved the feat three times.
• This is Salzburg's 56th UEFA Europa League match, group stage to final; only Spanish clubs Villarreal (62) and Athletic Club (60) have played more. Their tally of 29 wins is bettered only by Villarreal (33), and their current sequence of 12 matches without defeat in the competition proper is second only to Atlético Madrid’s 15-match run from November 2011 to October 2012.
• Suspended for next game if booked: Hwang Hee-Chan, Munas Dabbur, Xaver Schlager, Stefan Lainer, Duje Ćaleta-Car (Salzburg); Sokratis Papastathopoulos, Ömer Toprak, André Schürrle, Julian Weigl (Dortmund).
• Salzburg's record in two UEFA penalty shoot-outs is W1 L1:
5-4 v Eintracht Frankfurt, 1993/94 UEFA Cup quarter-final
2-3 v Dinamo Minsk, 2015/16 UEFA Europa League play-off
• Dortmund's record in UEFA penalty shoot-outs is W2 L2:
6-5 v Auxerre, 1992/93 UEFA Cup semi-final
3-1 v Rangers, 1999/2000 UEFA Cup third round
2-4 v Club Brugge, 2003/04 UEFA Champions League third qualifying round
3-4 v Udinese, 2008/09 UEFA Cup first round
• Previously Salzburg's youth team boss, Marco Rose stepped up to the senior helm after predecessor Óscar García left in June, having led the club to victory in the 2016/17 UEFA Youth League. A defender with home-town club Leipzig, Hannover and Mainz, he has been on Salzburg's coaching staff since 2013.
• Peter Stöger was appointed to replace Peter Bosz as Dortmund coach on 10 December 2017 – a week after he was dismissed by Köln, where he had been in charge for four and a half years. A four-time league champion as a player in his native Austria, with 65 international caps, he moved to Germany after steering Austria Wien to the 2012/13 title.