Matches
11 September 2021
Panetolikos
0-0
-
Asteras
19 September 2021
Asteras
0-1
-
PAOK
22 September 2021
OFI
-
-
Asteras
26 September 2021
Asteras
-
-
Olympiacos
02 October 2021
Apollon Smyrnis
-
-
Asteras
Match postponed
02 October 2021
Volos
-
-
Asteras
16 October 2021
Asteras
-
-
Panathinaikos
Match postponed
23 October 2021
Giannina
-
-
Asteras
Match postponed
30 October 2021
Asteras
-
-
Lamia
Match postponed
06 November 2021
Ionikos
-
-
Asteras
Match postponed
20 November 2021
Asteras
-
-
Atromitos
27 November 2021
Aris
-
-
Asteras
04 December 2021
Asteras
-
-
AEK
11 December 2021
Asteras
-
-
Panetolikos
15 December 2021
PAOK
-
-
Asteras
18 December 2021
Asteras
-
-
OFI
05 January 2022
Olympiacos
-
-
Asteras
08 January 2022
Asteras
-
-
Volos
15 January 2022
Asteras
-
-
Apollon Smyrnis
22 January 2022
Panathinaikos
-
-
Asteras
29 January 2022
Asteras
-
-
Giannina
05 February 2022
Lamia
-
-
Asteras
12 February 2022
Asteras
-
-
Ionikos
19 February 2022
Atromitos
-
-
Asteras
26 February 2022
Asteras
-
-
Aris
05 March 2022
AEK
-
-
Asteras