Matches
16 August 2021
Villarreal
0-0
-
Granada
21 August 2021
Granada
1-1
-
Valencia
29 August 2021
Rayo Vallecano
4-0
-
Granada
13 September 2021
Granada
1-2
-
Betis
20 September 2021
Barcelona
1-1
-
Granada
23 September 2021
Granada
2-3
-
Real Sociedad
27 September 2021
Celta
1-0
-
Granada
03 October 2021
Granada
1-0
-
Sevilla
17 October 2021
Granada
-
-
Atlético
Match postponed
22 October 2021
Osasuna
1-1
-
Granada
28 October 2021
Granada
-
-
Getafe
01 November 2021
Levante
-
-
Granada
06 November 2021
Espanyol
-
-
Granada
21 November 2021
Granada
-
-
Real Madrid
28 November 2021
Athletic Club
-
-
Granada
05 December 2021
Granada
-
-
Alavés
12 December 2021
Cádiz
-
-
Granada
19 December 2021
Granada
-
-
Mallorca
02 January 2022
Elche
-
-
Granada
09 January 2022
Granada
-
-
Barcelona
19 January 2022
Getafe
-
-
Granada
23 January 2022
Granada
-
-
Osasuna
06 February 2022
Real Madrid
-
-
Granada
13 February 2022
Real Sociedad
-
-
Granada
20 February 2022
Granada
-
-
Villarreal