Matches
14 August 2021
Ajax
5-0
-
NEC
22 August 2021
Twente
1-1
-
Ajax
29 August 2021
Ajax
5-0
-
Vitesse
11 September 2021
Zwolle
0-2
-
Ajax
18 September 2021
Ajax
9-0
-
Cambuur
21 September 2021
Fortuna Sittard
-
-
Ajax
25 September 2021
Ajax
-
-
Groningen
03 October 2021
Ajax
-
-
Utrecht
16 October 2021
Heerenveen
-
-
Ajax
24 October 2021
Ajax
-
-
PSV
30 October 2021
Heracles
-
-
Ajax
07 November 2021
Ajax
-
-
Go Ahead Eagles
21 November 2021
RKC
-
-
Ajax
28 November 2021
Sparta
-
-
Ajax
02 December 2021
Ajax
-
-
Willem II
12 December 2021
Ajax
-
-
AZ Alkmaar
19 December 2021
Feyenoord
-
-
Ajax
22 December 2021
Ajax
-
-
Fortuna Sittard
16 January 2022
Utrecht
-
-
Ajax
23 January 2022
PSV
-
-
Ajax
06 February 2022
Ajax
-
-
Heracles
13 February 2022
Ajax
-
-
Twente
20 February 2022
Willem II
-
-
Ajax
27 February 2022
Go Ahead Eagles
-
-
Ajax
06 March 2022
Ajax
-
-
RKC
13 March 2022
Cambuur
-
-
Ajax
20 March 2022
Ajax
-
-
Feyenoord
03 April 2022
Groningen
-
-
Ajax
10 April 2022
Ajax
-
-
Sparta
24 April 2022
NEC
-
-
Ajax
01 May 2022
Ajax
-
-
Zwolle
08 May 2022
AZ Alkmaar
-
-
Ajax
11 May 2022
Ajax
-
-
Heerenveen
15 May 2022
Vitesse
-
-
Ajax