Matches
15 August 2021
Sevilla
3-0
-
Rayo Vallecano
23 August 2021
Getafe
0-1
-
Sevilla
28 August 2021
Elche
1-1
-
Sevilla
11 September 2021
Sevilla
-
-
Barcelona
Match postponed
19 September 2021
Real Sociedad
0-0
-
Sevilla
22 September 2021
Sevilla
3-1
-
Valencia
25 September 2021
Sevilla
2-0
-
Espanyol
03 October 2021
Granada
1-0
-
Sevilla
17 October 2021
Celta
0-1
-
Sevilla
24 October 2021
Sevilla
-
-
Levante
27 October 2021
Mallorca
-
-
Sevilla
30 October 2021
Sevilla
-
-
Osasuna
07 November 2021
Betis
-
-
Sevilla
21 November 2021
Sevilla
-
-
Alavés
28 November 2021
Real Madrid
-
-
Sevilla
05 December 2021
Sevilla
-
-
Villarreal
12 December 2021
Athletic Club
-
-
Sevilla
19 December 2021
Sevilla
-
-
Atlético
02 January 2022
Cádiz
-
-
Sevilla
09 January 2022
Sevilla
-
-
Getafe
19 January 2022
Valencia
-
-
Sevilla
23 January 2022
Sevilla
-
-
Celta
06 February 2022
Osasuna
-
-
Sevilla
13 February 2022
Sevilla
-
-
Elche
20 February 2022
Espanyol
-
-
Sevilla
27 February 2022
Sevilla
-
-
Betis
06 March 2022
Alavés
-
-
Sevilla
13 March 2022
Rayo Vallecano
-
-
Sevilla
20 March 2022
Sevilla
-
-
Real Sociedad
03 April 2022
Barcelona
-
-
Sevilla
10 April 2022
Sevilla
-
-
Granada
17 April 2022
Sevilla
-
-
Real Madrid
20 April 2022
Levante
-
-
Sevilla
01 May 2022
Sevilla
-
-
Cádiz
08 May 2022
Villarreal
-
-
Sevilla
11 May 2022
Sevilla
-
-
Mallorca
15 May 2022
Atlético
-
-
Sevilla
22 May 2022
Sevilla
-
-
Athletic Club