Matches
12 September 2020
Twente
2-0
-
Fortuna Sittard
20 September 2020
Feyenoord
1-1
-
Twente
25 September 2020
Twente
3-1
-
Groningen
03 October 2020
Twente
1-1
-
Emmen
17 October 2020
Willem II
0-3
-
Twente
24 October 2020
Utrecht
2-1
-
Twente
31 October 2020
Twente
5-1
-
Zwolle
07 November 2020
Den Haag
2-4
-
Twente
22 November 2020
Twente
1-1
-
PSV
27 November 2020
Twente
0-2
-
RKC
05 December 2020
Ajax
1-2
-
Twente
13 December 2020
Twente
1-3
-
AZ Alkmaar
19 December 2020
VVV
1-2
-
Twente
22 December 2020
Twente
0-2
-
Sparta
09 January 2021
Emmen
1-4
-
Twente
14 January 2021
Twente
1-3
-
Ajax
17 January 2021
Groningen
2-2
-
Twente
24 January 2021
Twente
0-1
-
VVV
28 January 2021
Sparta
0-0
-
Twente
31 January 2021
Twente
0-0
-
Heerenveen
06 February 2021
PSV
3-0
-
Twente
14 February 2021
Vitesse
0-2
-
Twente
21 February 2021
Twente
2-2
-
Feyenoord
27 February 2021
Heracles
2-2
-
Twente
06 March 2021
Twente
1-1
-
Willem II
13 March 2021
AZ Alkmaar
4-1
-
Twente
19 March 2021
Heerenveen
0-0
-
Twente
03 April 2021
Twente
1-2
-
Vitesse
10 April 2021
Zwolle
1-0
-
Twente
25 April 2021
Twente
1-2
-
Utrecht
01 May 2021
Fortuna Sittard
3-0
-
Twente
08 May 2021
Twente
1-1
-
Heracles
13 May 2021
RKC
2-1
-
Twente
16 May 2021
Twente
-
-
Den Haag
27 October 2020
Twente
1-3
-
De Graafschap