Real Betis Balompié want to conclude their UEFA Champions League debut season on a winning note while RSC Anderlecht just want to win.
• Betis gained their first UEFA Champions League win on Matchday 2 with a 1-0 win against these opponents in the Constant Vanden Stock stadium, courtesy of a 69th-minute goal from Ricardo Oliveira, the Brazilian who is now a long-term absentee with knee ligament damage.
• The goal came against the run of play but in an open encounter Betis had struck the woodwork three times, through Oliveira, a Miguel Ángel Lozano header and following a Joaquín Sánchez free-kick.
• The defeat underlined the Belgian side's difficulties and their fortunes have not improved, losing all five games in Group G and without posting a single goal to their name. Defeat would mean they have lost all six group games for the second season in a row, the first team to do so.
• Betis's inferior goal difference in the two respective games against Chelsea FC means they can not finish ahead of the English team even were they to win this game and Chelsea lose at home to Liverpool FC. They will take heart from a determined defensive display which earned them a point away to holders Liverpool two weeks ago, their fourth in their last two games.
Eighth season of competition
• This is the eighth season of UEFA competition for the hosts who have twice reached the quarter-finals of the UEFA Cup Winners' Cup, in 1977/78 and 1997/98. However, it is the first time Betis have a played a home game against a Belgian club in UEFA competition.
Early Spanish success
• Anderlecht's first match in Spain was a creditable 3-3 draw at Real Madrid CF in the preliminary round of the 1962/63 European Champion Clubs' Cup. They followed that with a 1-0 win in the home leg and another 1-0 home win against the same opponents in the quarter-finals of the 1965/66 competition. However, Madrid got their revenge in the return and went on to lift the trophy that season - oddly enough in a final staged in Brussels against FK Partizan.
Little joy in Spain
• Anderlecht arrive in Seville for Matchday 6 on a run of five straight away defeats against Spanish clubs. Overall, the Belgian team have won once, drawn once and lost seven times in nine previous visits.
• The only success gained by them in Spain was a 2-1 win at Valencia CF in the quarter-finals of the 1982/83 UEFA Cup, after current Anderlecht coach Franky Vercauteren had set them on their way with an early goal. The Belgian team won 5-2 on aggregate and went on to lift the trophy.