PSV Eindhoven were soundly beaten in their only previous meetings with Club Atlético de Madrid, although there is nothing between the sides after the round of 16 first leg.
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Thwarted by Club Atlético de Madrid in 2008/09, PSV Eindhoven will look to make amends as their first UEFA Champions League knockout round tie in nine years concludes.
• This time round, the teams head to Spain all square having drawn 0-0 in the first leg in Eindhoven on 24 February.
• In the 2008/09 group stage Atlético won 2-1 in Spain, thanks to first-half goals from Simão and Maxi Rodríguez. Danny Koevermans replied early in the second half to put the visitors back in the game.
• The lineups at the Vicente Calderón on 26 November 2008 were:
Atlético: Coupet, Seitaridis, Pernía, Heitinga (Pablo Ibáñez 51), Ujfaluši, Raúl García (Paulo Assunção 80), Maniche, Maxi Rodríguez, Simão, Agüero, (Sinama Pongolle 66), Forlán.
PSV: Isaksson, Salcido, Rodríguez, Bréchet, Pieters (Culina 46), Simons, Méndez (Nijland 86), Dzsudzsák, Koevermans, Afellay (Bakkal 28), Lazović.
• Atlético had earlier won 3-0 in Eindhoven.
• The 2014 runners-up lost their first home fixture this season 2-1 against SL Benfica. It was their first European defeat at the Vicente Calderón since a 2-0 reverse against FC Rubin in the UEFA Europa League round of 32 in February 2013.
• They followed that with home victories over FC Astana and Galatasaray AŞ to finish first in Group C.
• Last season the Rojiblancos beat Bayer 04 Leverkusen 1-0 in the round of 16 home leg after losing the away game by the same score and eventually won through on penalties. After a 0-0 home draw with Real Madrid CF in the quarter-finals they lost 1-0 away.
• Atlético have lost all four two-legged ties they have contested with Dutch clubs but have won four of the five home games.
• Their sole defeat came in the 1996/97 UEFA Champions League quarter-finals, going down 3-2 at home to AFC Ajax after a 1-1 draw away.
• They beat the same side 1-0 at home in the 1970/71 semi-finals but went out 3-1 on aggregate.
• Home and away, Atlético's record against Dutch opponents is W5 D2 L4.
• Atlético have won ten of the 12 UEFA competition ties in which they drew the first leg away from home, losing only to Derby County FC (1974/75 UEFA Cup second round, 2-2 away, 2-2 home, 6-7 penalties) and AFC Ajax in the 1996/97 UEFA Champions League quarter-finals (1-1 away, 2-3 home)
• The Spanish side's aggregate record when drawing the first leg away 0-0 is W2 L0 having beaten Celtic FC in the 1973/74 European Champion Clubs' Cup semi-finals (2-0 home) and SC Bastia in the 1972/73 European Cup Winners' Cup first round (2-1 home).
• Atlético's shoot-out record in UEFA competition is W1 L3:
6-7 v Derby County FC, 1974/75 UEFA Cup second round
1-3 v ACF Fiorentina, 1989/90 UEFA Cup first round
1-3 v Villarreal, 2004 UEFA Intertoto Cup final
3-2 v Leverkusen, 2014/15 UEFA Champions League round of 16
• The Dutch champions are in the knockout rounds for the first time since 2006/07, when they went out to Liverpool FC in the quarter-finals, losing 3-0 at home and 1-0 away. In the round of 16 they defeated Arsenal FC 1-0 at home before a 1-1 away draw.
• In Group B they failed to win any of their away games – losing 3-2 at PFC CSKA Moskva and 2-0 at VfL Wolfsburg while their visit to Manchester United FC ended 0-0 – but finished second on ten points.
• This is PSV's 13th away match against Spanish opposition and they are still seeking a first victory. Their record in Spain is W0 D4 L8; overall it is W4 D11 L10.
• Their five visits to Madrid have produced four defeats, the solitary draw coming in the first leg of the 1987/88 European Cup semi-final with Real Madrid which set up an away goals triumph for PSV after a goalless second leg. The Dutch club won the final on penalties against Benfica.
• PSV's aggregate record when drawing the home first leg in European competition is W3 L9. All three wins came after a goalless first game, although they have also suffered three aggregate defeats following a 0-0 home first-leg draw.
• PSV's shoot-out record in UEFA competition is W3 L2:
6-5 v Tottenham Hotspur FC, 2007/08 UEFA Europa League round of 16
4-2 v Olympique Lyonnais, 2004/05 UEFA Champions League round of 16
4-5 v Feyenoord, 2001/02 UEFA Cup quarter-finals
6-7 v Club Nacional, 1988 European-South American Cup
6-5 v SL Benfica, 1987/88 European Champion Clubs' Cup final
Coach and player links
• Simeone captained Argentina in a 2-1 defeat against Phillip Cocu's Netherlands in the 1998 FIFA World Cup quarter-final in Marseille.
• Cocu made 292 appearances for FC Barcelona between 1998 and 2005.
• He faced Atlético six times (W2 D2 L2) and was sent off in their 0-0 Liga draw at the Vicente Calderón in September 2003. Fernando Torres started the game for the home side as did current assistant coach Germán Burgos. Simeone was an unused substitute for the Rojiblancos.
• Played in Spain:
Héctor Moreno, RCD Espanyol (2011–15);
Andrés Guardado, RC Deportivo La Coruña (2007–12; scoring the winner in a 2-1 La Liga home win over Atleti on 21 November 2009) and Valencia (2012–14).
• International team-mates:
Yannick Carrasco & Maxime Lestienne (Belgium U-21)
• Carrasco and Nicolas Isimat-Mirin played together at AS Monaco FC in 2013/14.
• Gastón Pereiro (Uruguay) and Ángel Correa (Argentina) were on opposing sides in the 2015 South American Youth Championship final. Pereiro opened the scoring for Uruguay, but Correa scored the winner in Argentina's 2-1 victory.
• Óliver Torres is a booking away from a suspension.
• Simeone's side are eight games unbeaten in all competitions following a 3-0 win against RC Deportivo La Coruña on 12 March.
• Carrasco, who missed the first leg with a right ankle injury, marked his comeback with a goal in the 3-1 win at Valencia on 6 March.
• After going five games without a goal, Antoine Griezmann has scored in each of his last four appearances.
• Luciano Vietto has not scored since matchday six.
• Stefan Savić (thigh) and Tiago (leg) are out.
• Guardado and Jeffrey Bruma are a booking away from a ban. Luuk de Jong returns from suspension, while Pereiro begins a one-game ban of his own after being dismissed in the first leg.
• PSV's run of ten successive Eredivisie wins ended with a 1-1 draw against sc Heerenveen on 12 March. Cocu's side went into that match having not conceded since the 58th minute of their 3-1 home defeat by FC Utrecht in the Dutch Cup quarter-finals on 4 February.
• Jetro Willems scored his first goal of the season in the 3-0 victory at FC Groningen on 5 March.
• Jeroen Zoet was voted UEFA.com's UEFA Champions League Player of the Week for his first-leg performance against Atlético.