Monaco have never lost to Bayer Leverkusen in four previous matches, and the Ligue 1 side will aim to keep it that way when the Group E rivals meet at the Stade Louis II.
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AS Monaco FC will look to build on their winning start at Wembley when they host Group F rivals Bayer 04 Leverkusen on matchday two.
• Monaco are unbeaten in four previous matches against Leverkusen (W3 D1).
• Monaco earned 1-0 home and away victories over Leverkusen in the 2014/15 UEFA Champions League group stage, when both teams qualified for the knockout stage. João Moutinho scored the only goal at the Stade Louis II, with Lucas Ocampo the matchwinner at the BayArena.
• The line-ups in Monaco on 16 September 2014 were:
Monaco: Subašić, Fabinho, Carvalho (Wallace 90+4), Raggi, Kurzawa, Kondogbia, Toulalan, Moutinho, Carrasco (Dirar 86), Ocampos (Bernardo Silva 57), Berbatov.
Leverkusen: Leno, Jedvaj (Donati 65), Toprak (Reinartz 71), Spahić, Boenisch, Bender (Drmic 75), Castro, Bellarabi, Çalhanoğlu, Son, Kiessling.
• The clubs first met in the 1997/98 group stage and ended level on points at the top of their section. Monaco won the head-to-head duel, winning 4-0 at home – Thierry Henry and Victor Ikpeba both scoring twice – and coming from two goals down to draw 2-2 away, with Henry hitting the equaliser.
• Monaco won only one of three home games in last season's UEFA Europa League (W1 D1 L1), against Qarabağ FK of Azerbaijan.
• They have won their last four home matches against Bundesliga opposition.
• Their overall record against German visitors to the principality is W4 D2 L1.
• Monaco lost the 1992 European Cup Winners' Cup final 2-0 against SV Werder Bremen in Lisbon.
• Leverkusen's record on the road in Europe last term was W1 D1 L4. That solitary win came at Sporting Clube de Portugal in the UEFA Europa League round of 32 (1-0).
• Leverkusen have won once in France in seven visits (two draws, four defeats). Ulf Kirsten earned them a 1-0 success at Olympique Lyonnais in the 2001/02 UEFA Champions League first group stage.
• Admir Mehmedi scored for Switzerland in a 2-0 win over Moutinho's Portugal in their opening 2018 FIFA World Cup qualifier on 6 September.
• Mehmedi was on the losing Swiss side against Kamil Glik's Poland in the UEFA EURO 2016 round of 16, with Glik converting a penalty in the deciding shoot-out.
• Morgan De Sanctis played at Leverkusen for Udinese Calcio in a 2-1 win in the 1999/2000 UEFA Cup third round, albeit losing the tie on away goals (2-2 agg). He was on the AS Roma bench for last season's group fixtures against Leverkusen (4-4 away, 3-2 home).
• Javier Hernández scored in Mexico's 2-0 victory over France at the 2010 FIFA World Cup.
• Have played together:
De Sanctis & Tin Jedvaj (AS Roma, 2013/14)
Subašić & Jedvaj (Croatia)
• Falcao's header in the 3-0 home victory over Stade Rennais FC on 17 September was his first Ligue 1 goal since 24 August 2014.
• Monaco's seven-match winning streak was emphatically halted by OGC Nice in the Côte d'Azur derby on 21 September, Mario Balotelli scoring twice for the hosts in a 4-0 triumph. Monaco had Tiémoué Bakayoko dismissed late on.
• Falcao went to hospital for tests after becoming dazed in a collision near the end of the first half in Nice and missed the 2-1 home win against Angers SCO on Saturday.
• Nabil Dirar (left calf) has not featured since being substituted early on against Tottenham.
• Benjamin Mendy (thigh) returned to action at the weekend, having last played on 28 August.
• Four of Fabinho's five goals this term have been penalties – all eight of his goals in 2015/16 were spot kicks.
• Hernández's second Bundesliga hat-trick sealed a 3-2 success at 1. FSV Mainz 05 on Saturday.
• Hernández (L2-1 v Eintracht Frankfurt, 17 September, hit post) and Charles Aránguiz (0-0 v FC Augsburg, 21 September, wide) have missed penalties in Leverkusen's last three games.
• Recovered from a hip injury that blighted his pre-season, Stefan Kiessling made his comeback against Augsburg as a second-half substitute.
• Karim Bellarabi suffered a groin injury a minute into the 3-1 victory over Hamburger SV on 10 September and will be out for the rest of the year having undergone surgery.
• Vladlen Yurchenko will be sidelined until October after sustaining a calf injury in training while on international duty earlier this month.