Can Lionel Messi score his 500th career goal? Can Antoine Griezmann strike in a fifth successive Atlético game? Can Paulo Dybala rescue Juve? UEFA.com teases out the week's sub-plots.
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Can Griezmann make it five from five?
"I play with a lot of freedom – hopefully I can carry on in the same vein," said Atlético Madrid's Antoine Griezmann, who having scored in all four of his Liga outings since the 0-0 first-leg draw at PSV, can make it five from five in all competitions in the rematch. The Dutch side's ten-game winning streak in the Eredivisie ended with Saturday's 1-1 draw against Heerenveen, Jeroen Zoet conceding his first goal in 603 minutes in all competitions. "It is a nice detail but I would prefer to win a trophy," the goalkeeper noted.
Atlético v PSV, Tuesday
Agüero chasing City history
Frustrated by Norwich City at the weekend, Sergio Agüero will face injury-sapped Dynamo Kyiv looking to claim his spot in the top ten of Manchester City's all-time scorers. The 27-year-old has struck 128 times since joining in 2011 and is two goals shy of tenth-placed Frank Roberts, with Billy Gillespie and Fred Tilson on 132 goals in joint eighth. "It would be a major achievement," said Agüero, whose team are 3-1 up from the away leg. "But I'd rather focus on my next goal rather than the ones I've scored and the ones I might score in the future."
Manchester City v Dynamo Kyiv, Tuesday
Dybala giving Juve hope
After getting his first UEFA Champions League goal in the 2-2 first-leg draw with Bayern, Juventus forward Paulo Dybala registered a wonderful goal against Sassuolo on Friday – his 14th of the season in Serie A. "Nobody has shown such a mix of technique and personality at 22," former Juve coach Fabio Capello told Gazzetta dello Sport. "In Italy he has already established himself as a top player – now he just needs to do it in Europe." Can he make that mark against a Bayern side with a shrinking injury list, who could afford to rest Arjen Robben, Douglas Costa and Arturo Vidal at the weekend?
Bayern v Juventus, Wednesday
Messi in hungry mood
Lionel Messi has netted 23 times in 18 appearances in 2016, and requires only three more to get to 500 for club and country. Though he missed a penalty in Saturday's 6-0 mauling of Getafe, he made amends with a superb free-kick. It is not the sort of form that offers Arsenal much hope as they come to Camp Nou 2-0 down. "It's 95% for them and 5% for us," manager Arsène Wenger noted of his team's chances, the Gunners travelling with heads bowed low, having been dumped out of the FA Cup by Watford on Sunday.
Barcelona v Arsenal, Wednesday