The inaugural group stage is in full swing; here's a taste of what's coming up next.
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The inaugural UEFA Europa Conference League group stage enters its home stretch on Matchday 4 with Roma and Tottenham out to make amends for surprise defeats last time out.
Enterprise Rent-A-Car presents UEFA.com's guide to the stand-out stories.
Thursday 4 November
Group A: LASK vs Alashkert, Maccabi Tel-Aviv vs HJK Helsinki
Group B: Gent vs Partizan, Flora Tallinn vs Anorthosis Famagusta
Group C: Zorya Luhansk vs CSKA-Sofia, Roma vs Bodø/Glimt
Group D: Randers vs Jablonec, AZ Alkmaar vs CFR Cluj
Group E: Union Berlin vs Feyenoord, Slavia Praha vs Maccabi Haifa
Group F: Lincoln Red Imps vs Slovan Bratislava, PAOK vs Copenhagen
Group G: Rennes vs Mura, Tottenham vs Vitesse
Group H: Kairat Almaty vs Qarabağ, Omonoia vs Basel
What to look out for?
Roma out for revenge after humiliation in Norway
"The positive thing from now on is that nobody will ask me why I always use the same players," said José Mourinho after rotating his Roma squad at Bodø/Glimt on Matchday 3 led to one of the heaviest defeats of his career. The Norwegian champions became the first side to put six past a Mourinho team in the Portuguese boss's 1,008th game as a manager. Disbelief and wild celebrations greeted the hosts' success, but the players were not involved, double-goalscorer Erik Botheim saying afterwards: "I am going home to put my feet up, recover and eat apples and bananas." Bodø/Glimt are a point clear of Roma at the top of Group C: will they have a fruitful return leg in Italy?
Spurs on the comeback trail
Tottenham's 1-0 loss at Vitesse last time out was not quite as eye-catching a result as Roma's reversal, but the defeat was another reminder that even the biggest names in the UEFA Europa Conference League can expect complications if they rest players on a Thursday night. Pre-tournament favourites, Spurs now sit third in Group G, two points outside the qualifying spots. To make matters more complicated, they parted company with manager Nuno Espírito Santo on Monday, with former Juventus, Italy and Chelsea boss Antonio Conte appointed as his replacement a day later.
Buffalo charging toward last 16
A number of clubs can secure top-two finishes on Matchday 4 but only Gent can make certain of a round of 16 berth. The sole side with a 100% record in the group stage, they will finish top of Group B if they can follow up their 1-0 win at Partizan with a victory at home. "My players showed a top mentality from the first minute to the last," said the Buffalos' coach Hein Vanhaezebrouck, who has been reminding his players that the new competition is not to be underestimated: "I told my squad these are Europa League-level matches and that it is up to us to show that we can handle that." All going well so far.
• Maccabi Tel-Aviv are the leading marksmen in the group stage with ten goals after a 5-0 triumph at HJK Helsinki (the biggest away win in the groups to date), while midfielder Gavriel Kanichowsky is one of four players to have hit three goals so far. Can Patrick van Leeuwen's side maintain that pace for the rest of the campaign?
• Having lifted the European Cup in 1970 and the UEFA Cup in 1974 and 2002, Feyenoord have had their hands on the two most prestigious current trophies in European club football; they will become the first team to complete a clean sweep if they add the UEFA Europa Conference League to their set this season.
14/16 September: Matchday 1
30 September: Matchday 2
21 October: Matchday 3
4 November: Matchday 4
25 November: Matchday 5
9 December: Matchday 6
13 December: Knockout round play-off draw
17 & 24 February: Knockout round play-offs
25 February: Round of 16 draw
10 & 17 March: Round of 16
18 March: Quarter-final & semi-final draws
7 & 14 April: Quarter-finals
28 April & 5 May: Semi-finals
25 May: Final (National Arena, Tirana)