CSKA Moskva are without a win in their last three home games against French opposition, although Lyon – continuing their bid for a final place in their own city – have never won in Russia.
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The only one of the three remaining Russian clubs to start the round of 16 at home, CSKA Moskva welcome 2017/18 final host club Lyon to the Russian capital.
• Third in their UEFA Champions League group during the autumn, CSKA overcame Crvena zvezda in the round of 32, a goalless draw in Belgrade preceding a 1-0 win in Moscow, with Alan Dzagoev scoring the all-important goal on the stroke of half-time.
• Lyon were one of only three clubs to emerge victorious from the round of 32 having played the second leg away, adding a 1-0 win in Spain against Villarreal to a 3-1 first-leg success at the Parc OL. They were runners-up to Atalanta in the group phase.
• The two clubs have never met in UEFA competition.
• CSKA's record against French clubs in Europe is W4 D3 L5, with two wins, two draws and two defeats in Russia. They have not defeated French opposition at home in three attempts since beating Auxerre 4-0 in the quarter-final first leg of the 2004/05 UEFA Cup – a competition they went on to win.
• The Army Men's heaviest European defeat was against Ligue 1 opponents, Marseille overwhelming them 6-0 in the inaugural UEFA Champions League group stage in 1992/93 on the club's first visit to France.
• Lyon have yet to win in three trips to Russia – all at various stages of the UEFA Champions League. Having drawn 1-1 away to Spartak Moskva (2000/01 second group stage) and Rubin Kazan (2011/12 play-offs), they lost 3-1 to Zenit on their most recent visit, in the 2015/16 group stage, also losing the return at home (0-2).
• CSKA lost their opening two home games in this season's UEFA Champions League group stage – 1-4 against Manchester United, 0-2 against Basel – before defeating Benfica 2-0 in Moscow on matchday five and then prevailing 1-0 against Crvena zvezda to win their round of 32 tie by the same aggregate score.
• That victory over Crvena zvezda was the Russian side's first in six home matches in springtime European competition (D3 L2); they have scored four goals over that stretch while conceding five. It was also their first victory in four UEFA Europa League home fixtures, play-offs included (D1 L2).
• The Moscow side's last European knockout phase involvement was a UEFA Champions League round of 16 tie with Real Madrid in 2011/12, which they lost 5-2 on aggregate (1-1 home, 1-4 away). Their only previous appearance in the UEFA Europa League round of 16 dates back to 2010/11, when they were defeated home (0-1) and away (1-2) by eventual winners Porto.
• CSKA were runners-up to city rivals Spartak Moskva in last season's Russian Premier League. To reach the UEFA Champions League group stage they came through two qualifying rounds, defeating both AEK Athens and Young Boys 3-0 on aggregate.
• Lyon conceded one goal in each of their group stage away matches (W1 D1 L1) before winning 1-0 at Villarreal in the round of 32 – their first clean sheet in eight European away fixtures (W3 D1 L4).
• The win at Villarreal ended a run of three successive UEFA Europa League knockout defeats on the road. It was also only Lyon's second win in 18 away games during the spring knockout phase of European competition (D3 L13).
• This is Lyon's third appearance in the UEFA Europa League round of 16. Their previous two ties at this stage both ended in victory, although they lost both away games 2-1 – against Viktoria Plzeň in 2013/14 (4-1 home) and Roma in 2016/17 (4-2 home).
• Lyon were UEFA Europa League semi-finalists last season, when they lost to Ajax having transferred from the UEFA Champions League group stage. They ensured a return to this season's UEFA Europa League group stage by finishing fourth in Ligue 1.
Links and trivia
• Lyon are the only team in this season's round of 16 who were also present at the same stage 12 months ago. They are also the only French club ever to have reached the quarter-finals of the UEFA Europa League, having done so twice.
• CSKA goalkeeper Igor Akinfeev has played every minute of his team's European campaign this season, keeping seven clean sheets in 12 matches. Team-mate Mario Fernandes has also been ever-present.
• Akinfeev's counterpart, Anthony Lopes, has likewise been on the field for every minute of Lyon's eight-match UEFA Europa League journey, conceding just five goals and never more than one in a game.
• Lyon's Memphis Depay played twice against CSKA for Manchester United in the 2015/16 UEFA Champions League group stage: a 1-1 away draw in Khimki, and a 1-0 home win in Manchester.
• This season's UEFA Europa League final, on 16 May 2018, will be staged in Lyon's home stadium.
• Lyon are one of only four teams in the UEFA Europa League round of 16 to have never played in a European final, the others being RB Leipzig, Viktoria Plzeň and Lokomotiv Moskva.
• Lyon's Marçal is available after being suspended for the round of 32 second leg.
• CSKA's Aleksandr Golovin returns from a one-match ban, but team-mate Vasili Berezutski serves a suspension for this encounter.
• Suspended for next match if booked: Pontus Wernbloom (CSKA); Marcelo, Nabil Fekir (Lyon)
• Appointed by CSKA to replace long-serving coach Leonid Slutski in December 2016, Viktor Goncharenko was only 39 at the time, but he had earned a growing reputation in Russian football, notably while serving as Slutski's assistant. He made his name as a coach in his native Belarus at BATE Borisov, winning five straight titles and leading the club into the UEFA Champions League group stage on three occasions.
• Born in Lyon, Bruno Génésio came through the club's ranks as a midfielder, playing for the senior side from 1985 to 1995 before seeing out his career for one season at Martigues. He returned to the club's coaching staff in 2007 and served as assistant boss for four years before taking sole command in December 2015 when he replaced Hubert Fournier.