Having had their winning run ended at PFC CSKA Moskva, Real Madrid CF will be keen to bounce back against opponents who have triumphed on both their previous visits to Spain.
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Real Madrid CF won all six of their group games and looked on course for a seventh victory in the first leg of their round of 16 tie at PFC CSKA Moskva only to be pegged back at the last.
• Cristiano Ronaldo's 28th-minute strike in Moscow gave Madrid the lead, but CSKA debutant Pontus Wernbloom levelled with the final kick of the game to stretch the Russian side's unbeaten record against Spanish sides to six games, home and away.
• At this stage two years ago CSKA put out another Spanish team, Sevilla FC, with a 2-1 away win thanks to goals from Tomáš Necid and Keisuke Honda. The home game had again ended 1-1, Mark González scoring CSKA's equaliser.
• Ahead of the first meeting between these teams on Spanish soil, Madrid have lost just one of the nine home fixtures against Russian opponents, going down 3-1 to FC Spartak Moskva in the 1990/91 European Champion Clubs' Cup quarter-final. They won seven of the other eight games.
• José Mourinho's team scored 13 goals in winning all their home matches in Group D, conceding only two, and became only the fifth side to win all six games in a UEFA Champions League group stage.
• Madrid have won all but one of the 21 previous UEFA competition ties in which they earned a first-leg away draw; the sole blemish came in that 1990/91 tie with Spartak, when they drew 0-0 away.
• The Spanish side have therefore won all nine of the ties in which they drew 1-1 away in the first leg, most recently against Olympique Lyonnais in last season's round of 16.
• Mourinho's FC Internazionale Milano team prevailed 1-0 home and away against CSKA in their 2009/10 quarter-final on their way to lifting the trophy. It was the furthest the Moscow club have progressed in the competition.
• Before the Sevilla game CSKA had only faced two opponents from Spain, beating RC Deportivo La Coruña 3-0 in the 2008/09 UEFA Cup group stage in Moscow. One of their most memorable results came in their first visit to Spain in the 1992/93 UEFA Champions League second round, six months after FC Barcelona had lifted the trophy for the first time, when CSKA beat them 3-2 at the Camp Nou for a 4-3 aggregate win.
• The 2004/05 UEFA Cup winners owed their place in the last 16 to their form on their travels, particularly a 2-1 matchday six win at Inter which took CSKA from last to second place in Group B. They drew at LOSC Lille Métropole (2-2) and Trabzonspor AŞ (0-0).
• Those triumphs against Barcelona and Sevilla are the only times CSKA have drawn at home in the first leg of a UEFA competition tie and gone through to the next stage; they lost the other three ties.
• Igor Akinfeev, Sergei Ignashevich and Vasili Berezutski all played for Russia against a Spain team featuring Sergio Ramos, Xabi Alonso and Iker Casillas at UEFA EURO 2008. Spain won 4-1 in the opening group fixture and then 3-0 in the semi-finals.
• Ronaldo and Ricardo Carvalho helped Portugal beat Russia 2-0 at UEFA EURO 2004 with Evgeni Aldonin on the losing team.
• Ronaldo scored twice in a 7-1 FIFA World Cup qualifying defeat of Russia in Lisbon in October 2004. Carvalho, Ignashevich and Aldonin all started; all four started the return in Moscow in September 2005 which ended 0-0, Akinfeev and the Berezutski brothers also playing.
• Mourinho met CSKA in the 2004/05 group stage, his first season at Chelsea FC. The London club, including Carvalho, won 2-0 at home and 1-0 away.
• In six Liga encounters against Madrid, González appeared on the winning side just once, scoring the decisive goal as Real Betis Balompié came from behind to win 2-1 at home in 2008. He also got Real Sociedad de Fútbol's equaliser in a 1-1 draw at the Santiago Bernabéu in 2006.
• Kaká played for Brazil in a friendly international against Russia in Moscow in March 2006 which the visitors won 1-0. Akinfeev, Ignashevich, Aldonin and the Berezutskis all appeared for the hosts.