Atlético Madrid are through and looking to clinch first place in Group D while visitors PSV Eindhoven have their sights on a UEFA Europe League spot despite some domestic stumbles.
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- Atlético are through and will clinch Group D if they better Bayern's result in Rostov
- A UEFA Europa League round of 32 place is PSV's best remaining outcome
- The Rojiblancos prevailed 1-0 in Eindhoven on matchday one
- Atleti have lost their last two games without scoring
Atlético: Oblak; Vrsaljko, Godín, Giménez, Filipe Luís; Gaitán, Koke, Gabi, Carrasco; Griezmann, Gameiro.
Out: Augusto Fernández (knee), Alessio Cerci (knee)
Misses next match if booked: Filipe Luís
PSV: Zoet; Arias, Isimat-Mirin, Schwaab, Moreno, Willems; Pröpper, Ramselaar, Narsingh; Pereiro, L De Jong.
Out: Guardado (hamstring), Hendrix (knee), Locadia (groin), Brenet (ankle)
Diego Simeone, Atlético coach
We are working along the same lines as always. We know the difficulties that PSV can cause us. We are focused on tomorrow and we want to finish top of the group, of course. Without totally forgetting the past few games we've had, we're focused on the here and now.
Phillip Cocu, PSV coach
I don't see too many differences between this Atlético side and the one last season. They press you high, defend compactly between the lines and it's hard to create chances against them.
Atlético will want to win against us tomorrow, that goes without saying. We aren't able to get to the knockout stage but we can continue in Europe and we want to get a result, a draw or maybe better. It will be hard but this is the Champions League group stage so there's no easy games.
Atlético 0-3 Real Madrid (Ronaldo 23 71pen 77)
Unbeaten in their first 11 games of the campaign, Atlético have now lost three of their last five. This was their first Liga home defeat in 23 matches, a run dating back to September 2015.
Willem II 0-0 PSV
PSV failed to score for the first time since September and are now without a win in their last three outings in all competitions.
Form guide (all competitions, most recent first)
Reporter's view: Joe Walker (@UEFAcomJoeW)
The only side left in this season's competition with a 100% record, Atlético will be confident of maintaining that – and their superb European home form – against PSV. The three games these teams have played in 2016, including 30 minutes' extra time last term, have produced just one goal, so do not expect fireworks. However, with Atlético keen to extend their run, there should be entertainment aplenty. The one major decision for Simeone is whether or not he persists with Torres up front or moves Carrasco alongside Griezmann.
Did you know?
Simeone captained Argentina in a 2-1 loss to Cocu's Netherlands in a 1998 FIFA World Cup quarter-final in Marseille. Read more in our extensive match background.