Follow the draw as it happens here on Monday 12 December, with commentary and live video.
13:00CET, 12 December, Nyon
- Seeded: Ajax (NED), APOEL (CYP), Beşiktaş (TUR)*, Fenerbahçe (TUR), Fiorentina (ITA), Genk (BEL), København (DEN)*, Lyon (FRA)*, Osmanlıspor (TUR), Roma (ITA), Schalke (GER), Shakhtar Donetsk (UKR), Sparta Praha (CZE), St-Étienne (FRA), Tottenham Hotspur (ENG)*, Zenit (RUS)
- Unseeded: Anderlecht (BEL), Astra Giurgiu (ROU), Athletic Club (ESP), AZ Alkmaar (NED), Celta Vigo (ESP), Gent (BEL), Hapoel Beer-Sheva (ISR), Krasnodar (RUS), Legia Warszawa (POL)*, Ludogorets Razgrad (BUL)*, Manchester United (ESP), Borussia Mönchengladbach (GER)*, Olympiacos (GRE), PAOK (GRE), Rostov (RUS)*, Villarreal (ESP)
* Transferring from UEFA Champions League group stage
• There will be two pots for the round of 32 draw: the 12 group winners and the four best third-ranked teams in the UEFA Champions League group stage are seeded.
• The group winners and four best third-placed teams in the UEFA Champions League will be drawn against the 12 group runners-up and the remaining third-placed UEFA Champions League sides.
• The seeded teams will be at home in the second leg.
• No team can play a club from their UEFA Europa League group or a side from the same association and due to decisions of the UEFA Executive Committee and UEFA Emergency Committee, teams from Russia and Ukraine cannot meet.
• Games will be played in principle on Thursdays 16 and 23 February at 19:00CET and 21:05CET, with the exact schedule confirmed after the draw.