Internazionale are on a four-game European losing streak after defeats by two-goal margins in their opening Group K games, and need a lift as they welcome miserly Southampton.
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Internazionale will look to end a damaging run of European defeats as they welcome Southampton on matchday three, the English side yet to concede in Group K.
• The teams are meeting for the first time in what is Southampton's first encounter with Serie A opponents.
• Inter's 28 games against English clubs have yielded stats of W13 D4 L11 (W9 D3 L2 in Milan). They have won their three most recent home fixtures with Premier League visitors.
• Internazionale are on a four-match European losing streak after defeats by two-goal margins in their opening Group K games.
• UEFA Cup winners in 1991, 1994 and 1998, Inter have successfully negotiated both of their previous UEFA Europa League group stage campaigns.
• Southampton, Shakhtar Donetsk and Beer-Sheva are the only sides still to concede in this season's group stage coming into matchday three.
• Southampton have won just once in their last seven European away fixtures (W1 D3 L3) – a 2-0 success at Vitesse in last season's UEFA Europa League third qualifying round. They failed to score in the other six.
• Southampton are debuting in a UEFA competition group stage.
Links and trivia
•The journey from Southampton to Milan is about 1,000km.
• Inter have played more UEFA Cup and UEFA Europa League games than any other club, 177 – and have also won (87) and drawn (43) the most matches.
• Former team-mates:
Éver Banega (Inter) & Oriol Romeu (Southampton) – Valencia, 2013–14
• Inter's Gary Medel (Cardiff City, 2013–14) and Davide Santon (Newcastle, 2011–15) have Premier League experience, while reserve goalkeeper Tommaso Berni was once on the books of Wimbledon.
• Hired by Inter this summer, Frank de Boer had managed Ajax since 2010, and in 2014 became the first coach to lead the club to four successive Eredivisie titles. The former defender also won the UEFA Cup and UEFA Champions League as an Ajax player.
• Frenchman Claude Puel was appointed by Southampton in June. A one-club man, he spent his entire playing career with Monaco, claiming two league titles as a player and one more as a coach. He has since held the reins at LOSC, Lyon and – in the past four seasons – Nice.