Beşiktaş have yet to lose a European home game at their new stadium, but a draw will be no use to them as they welcome Lyon, trailing 2-1 after conceding two late goals in France.
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Beşiktaş are within sight of a first major European semi-final, but could do with a first clean European sheet at their new stadium as they welcome Lyon.
• Lyon struck twice late on in the first leg as they beat Beşiktaş 2-1 in the sides' first game in UEFA competition.
• Beşiktaş are unbeaten at home against French sides (W2 D1) but have now lost all four of their previous games in France.
• Lyon's record in 11 games against Turkish teams is W6 D1 L4 (W2 D1 L2 away). Lyon have not faced Turkish opposition since the 2004/05 UEFA Champions League group stage, when they beat Fenerbahçe 3-1 in Istanbul and 4-2 at home.
• The Black Eagles have yet to lose in five European games at the Beşiktaş Park (W2 D3), but have also never kept a UEFA clean sheet at their new home. They are unbeaten in eight European home games overall (W3 D5).
• Lyon's away record in Europe this season is W2 D1 L2. They have scored at least once in all but one of those games.
• Lyon have scored 18 goals since entering the competition in the round of 32; their average of 3.6 goals per game is the highest of any side in this season's competition
• Beşiktaş last reached a UEFA quarter-final in the 2002/03 UEFA Cup, losing to Lazio. They have never been in a semi-final.
• Lyon's last semi-final was in the 2009/10 UEFA Champions League, where they were eliminated by Bayern München. No French team has won the UEFA Cup or UEFA Europa League.
Links and trivia
• The journey from Lyon to Istanbul is around 2,000km.
• Beşiktaş's Vincent Aboubakar and Marcelo are serving suspensions along with Lyon's Rafael.
• Misses next match if booked:-
Beşiktaş: Tolgay Arslan, Caner Erkin, Oğuzhan Özyakup
Lyon: Maxwel Cornet, Sergi Darder, Christophe Jallet, Alexandre Lacazette, Lucas Tousart.
• Beşiktaş are the only domestic champions left in the UEFA Europa League this season.
• Beşiktaş's Vincent Aboubakar and Lyon's Nicolas Nkoulou are international team-mates with Cameroon. Aboubakar played in Ligue 1 from 2010 to 2015 with Valenciennes and Lorient.
• Beşiktaş's Serbian defender Duško Tošić also has Ligue 1 experience, having helped Sochaux win the 2006/07 French Cup in his lone full season in France.
• Beşiktaş coach Şenol Güneş famously guided Turkey to third place at the 2002 FIFA World Cup. A goalkeeper who spent the majority of his playing career at home-town club Trabzonspor, he led Beşiktaş to the 2015/16 Turkish title in his first season in charge.
• Bruno Génésio took charge at Lyon in December 2015, but his links to the club go back much further. A local boy, he joined OL as a trainee in 1983 and represented Lyon as a midfielder from 1985 to 1995. He later worked as a scout and was assistant coach from 2011 to 2015.
• Beşiktaş won their only previous UEFA penalty shoot-out:
W 5-4 H v Liverpool (2014/15 UEFA Europa League round of 32)
• Lyon have lost both of their previous UEFA penalty shoot-outs:
L 4-2 A v PSV (2004/05 UEFA Champions League quarter-finals)
L 4-3 A v APOEL (2011/12 UEFA Champions League round of 16)