Matches
14 August 2021
Augsburg
0-4
-
Hoffenheim
22 August 2021
Hoffenheim
2-2
-
Union Berlin
27 August 2021
Dortmund
3-2
-
Hoffenheim
11 September 2021
Hoffenheim
0-2
-
Mainz
18 September 2021
Arminia
0-0
-
Hoffenheim
25 September 2021
Hoffenheim
3-1
-
Wolfsburg
02 October 2021
Stuttgart
3-1
-
Hoffenheim
15 October 2021
Hoffenheim
5-0
-
Köln
23 October 2021
Bayern
4-0
-
Hoffenheim
29 October 2021
Hoffenheim
2-0
-
Hertha
06 November 2021
Bochum
2-0
-
Hoffenheim
20 November 2021
Hoffenheim
2-0
-
Leipzig
27 November 2021
Fürth
3-6
-
Hoffenheim
04 December 2021
Hoffenheim
3-2
-
Frankfurt
11 December 2021
Freiburg
1-2
-
Hoffenheim
15 December 2021
Leverkusen
2-2
-
Hoffenheim
18 December 2021
Hoffenheim
1-1
-
Mönchengladbach
08 January 2022
Hoffenheim
3-1
-
Augsburg
15 January 2022
Union Berlin
2-1
-
Hoffenheim
22 January 2022
Hoffenheim
-
-
Dortmund
05 February 2022
Mainz
-
-
Hoffenheim
13 February 2022
Hoffenheim
-
-
Arminia
19 February 2022
Wolfsburg
-
-
Hoffenheim
25 February 2022
Hoffenheim
-
-
Stuttgart
06 March 2022
Köln
-
-
Hoffenheim
12 March 2022
Hoffenheim
-
-
Bayern
19 March 2022
Hertha
-
-
Hoffenheim
02 April 2022
Hoffenheim
-
-
Bochum
09 April 2022
Leipzig