Matches
12 September 2021
AEK Larnaca
2-1
-
Omonoia
20 September 2021
Omonoia
2-1
-
Doxa
26 September 2021
Omonoia
1-1
-
Pafos
03 October 2021
Olympiakos
1-0
-
Omonoia
17 October 2021
Omonoia
1-0
-
Apollon
25 October 2021
P.A.E.E.K.
1-0
-
Omonoia
29 October 2021
Omonoia
0-1
-
Anorthosis
07 November 2021
Ethnikos Achnas
0-2
-
Omonoia
21 November 2021
Omonoia
3-0
-
Aris Limassol
05 December 2021
AEL
0-1
-
Omonoia
13 December 2021
Omonoia
1-1
-
AEK Larnaca
19 December 2021
Doxa
2-1
-
Omonoia
22 December 2021
Omonoia
1-0
-
AEL
26 December 2021
APOEL
4-2
-
Omonoia
05 January 2022
Pafos
1-1
-
Omonoia
10 January 2022
Omonoia
1-0
-
Olympiakos
16 January 2022
Apollon
2-0
-
Omonoia
24 January 2022
Omonoia
-
-
P.A.E.E.K.
29 January 2022
Anorthosis
-
-
Omonoia
05 February 2022
Omonoia
-
-
Ethnikos Achnas
12 February 2022
Aris Limassol
-
-
Omonoia
19 February 2022
Omonoia
-
-
APOEL
20 January 2022
Xylotympou
-
-
Omonoia
01 February 2022
Omonoia
-
-
Xylotympou