Matches
22 August 2021
Roma
3-1
-
Fiorentina
28 August 2021
Fiorentina
2-1
-
Torino
11 September 2021
Atalanta
1-2
-
Fiorentina
18 September 2021
Genoa
1-2
-
Fiorentina
21 September 2021
Fiorentina
1-3
-
Inter
26 September 2021
Udinese
0-1
-
Fiorentina
03 October 2021
Fiorentina
1-2
-
Napoli
18 October 2021
Venezia
1-0
-
Fiorentina
24 October 2021
Fiorentina
3-0
-
Cagliari
27 October 2021
Lazio
1-0
-
Fiorentina
31 October 2021
Fiorentina
3-0
-
Spezia
06 November 2021
Juventus
1-0
-
Fiorentina
20 November 2021
Fiorentina
4-3
-
Milan
27 November 2021
Empoli
2-1
-
Fiorentina
30 November 2021
Fiorentina
3-1
-
Sampdoria
05 December 2021
Bologna
2-3
-
Fiorentina
11 December 2021
Fiorentina
4-0
-
Salernitana
19 December 2021
Fiorentina
2-2
-
Sassuolo
22 December 2021
Verona
1-1
-
Fiorentina
06 January 2022
Fiorentina
-
-
Udinese
Match suspended
10 January 2022
Torino
4-0
-
Fiorentina
17 January 2022
Fiorentina
6-0
-
Genoa
23 January 2022
Cagliari
1-1
-
Fiorentina
05 February 2022
Fiorentina
-
-
Lazio
14 February 2022
Spezia
-
-
Fiorentina
20 February 2022
Fiorentina
-
-
Atalanta
27 February 2022
Sassuolo
-
-
Fiorentina
06 March 2022
Fiorentina
-
-
Verona
13 March 2022
Fiorentina
-
-
Bologna