Matches
08 August 2021
Tikves
0-0
-
Shkëndija
15 August 2021
FK Borec Veles
2-1
-
Tikves
18 August 2021
Tikves
0-2
-
Akademija Pandev
22 August 2021
Rabotnicki
2-1
-
Tikves
28 August 2021
Tikves
1-1
-
Struga
12 September 2021
Tikves
0-2
-
Renova
19 September 2021
Bregalnica
2-0
-
Tikves
26 September 2021
Tikves
3-0
-
Makedonija
02 October 2021
Pelister
0-0
-
Tikves
16 October 2021
Tikves
0-1
-
Shkupi
24 October 2021
FK Skopje
2-1
-
Tikves
30 October 2021
Shkëndija
1-1
-
Tikves
06 November 2021
Tikves
2-1
-
FK Borec Veles
21 November 2021
Akademija Pandev
3-2
-
Tikves
28 November 2021
Tikves
2-0
-
Rabotnicki
05 December 2021
Struga
-
-
Tikves
08 December 2021
Renova
-
-
Tikves
12 December 2021
Tikves
-
-
Bregalnica
13 February 2022
Makedonija
-
-
Tikves
20 February 2022
Tikves
-
-
Pelister
27 February 2022
Shkupi
-
-
Tikves
06 March 2022
Tikves
-
-
FK Skopje
15 September 2021
FK Novaci
0-2
-
Tikves
20 October 2021
Shkupi
1-0
-
Tikves