Matches
15 August 2021
Mainz
1-0
-
Leipzig
21 August 2021
Bochum
2-0
-
Mainz
28 August 2021
Mainz
3-0
-
Fürth
11 September 2021
Hoffenheim
0-2
-
Mainz
18 September 2021
Mainz
0-0
-
Freiburg
25 September 2021
Leverkusen
1-0
-
Mainz
03 October 2021
Mainz
1-2
-
Union Berlin
16 October 2021
Dortmund
3-1
-
Mainz
22 October 2021
Mainz
4-1
-
Augsburg
30 October 2021
Arminia
1-2
-
Mainz
05 November 2021
Mainz
1-1
-
Mönchengladbach
21 November 2021
Mainz
1-1
-
Köln
26 November 2021
Stuttgart
2-1
-
Mainz
04 December 2021
Mainz
3-0
-
Wolfsburg
11 December 2021
Bayern
2-1
-
Mainz
14 December 2021
Mainz
4-0
-
Hertha
18 December 2021
Frankfurt
1-0
-
Mainz
08 January 2022
Leipzig
4-1
-
Mainz
15 January 2022
Mainz
1-0
-
Bochum
22 January 2022
Fürth
-
-
Mainz
05 February 2022
Mainz
-
-
Hoffenheim
12 February 2022
Freiburg
-
-
Mainz
18 February 2022
Mainz
-
-
Leverkusen
26 February 2022
Union Berlin
-
-
Mainz
06 March 2022
Mainz
-
-
Dortmund
12 March 2022
Augsburg
-
-
Mainz
19 March 2022
Mainz
-
-
Arminia
02 April 2022
Mönchengladbach
-
-
Mainz
09 April 2022
Köln
-
-
Mainz