PSV were soundly beaten in their only previous meeting with Atlético de Madrid and on their return to the UEFA Champions League knockout rounds will be hoping to make amends.
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PSV Eindhoven's only previous home encounter with Club Atlético de Madrid ended in a decisive defeat and in their first UEFA Champions League knockout round fixture for nine years the hosts will be looking to make amends.
• The lineups at the PSV Stadium on 16 September 2008 were:
PSV: Isaksson, Salcido, Marcellis, Bréchet (Rodríguez 74), Pieters, Méndez, Simons, Culina (Bakkal 46), Amrabat, Koevermans, Afellay (Lazović 70).
Atlético: Leo Franco, Perea, Heitinga, Ujfaluši, Antonio López, Luis García, Paulo Assunção, Maniche (Banega 65), Simão, Agüero (Raúl García 63), Forlán (Sinama Pongolle 31).
• The Dutch champions are in the knockout rounds for the first time since 2006/07, when they went out to Liverpool FC in the quarter-finals, losing 3-0 at home and 1-0 away. In the round of 16 they defeated Arsenal FC 1-0 at home before a 1-1 away draw.
• In their 14th UEFA Champions League group stage campaign this season, they won all three home matches, beating Manchester United FC and PFC CSKA Moskva 2-1 and Wolfsburg 2-0 to finish second in Group B with ten points.
• PSV's 24 games against Spanish opponents have ended W4 D10 L10 (W4 D6 L2 at home – W0 D4 L8 in Spain).
• FC Barcelona are the only other Spanish side to have won at the PSV Stadion, prevailing 3-2 in the second leg of the 1995/96 UEFA Champions League quarter-final to complete a 5-4 aggregate triumph.
• The 2014 runners-up were unbeaten in their three group away games, helping them reach 13 points to win Group C with a three-point margin over SL Benfica.
• Diego Simeone's side began their sixth group stage campaign with a 2-0 victory at Galatasaray AŞ, drew 0-0 at FC Astana and then won 2-1 at Benfica.
• Last season the Rojiblancos lost their round of 16 away leg 1-0 at Bayer 04 Leverkusen, eventually going through on penalties after the same score at home. They lost 1-0 at Real Madrid CF, and by the same aggregate score, in the quarter-final second leg.
• Atlético have lost all four two-legged ties they have contested with Dutch clubs and have an unhappy record in the Netherlands.
• They surrendered a 1-0 first-leg lead when going down 3-0 to AFC Ajax on their first visit to the Netherlands for a European Champion Clubs' Cup semi-final in 1970/71. Atleti lost twice at FC Groningen in the 1980s and when they did finally avoid defeat on Dutch soil, against Ajax in the 1996/97 UEFA Champions League quarter-finals, they lost the return leg in Spain 3-2.
• Home and away, Atlético's record against Dutch opponents is: W5 D1 L4.
Coach and player links
• Simeone captained Argentina in a 2-1 defeat against Phillip Cocu's Netherlands in the 1998 FIFA World Cup quarter-final in Marseille.
• Cocu made 292 appearances for FC Barcelona between 1998 and 2005.
• He faced Atlético six times (W2 D2 L2) and was sent off in their 0-0 Liga draw at the Vicente Calderón in September 2003. Fernando Torres started the game for the home side as did current assistant coach Germán Burgos. Simeone was an unused substitute for the Rojiblancos.
• Played in Spain:
Hector Moreno, RCD Espanyol (2011–15);
Andrés Guardado, RC Deportivo La Coruña (2007–12; scoring the winner in a 2-1 La Liga home win over Atleti on 21 November 2009) and Valencia (2012–14).
• International team-mates:
Santiago Arias and Jackson Martínez (Colombia);
Yannick Carrasco & Maxime Lestienne (Belgium U-21)
• Yannick Carrasco and Nicolas Isimat-Mirin played together at AS Monaco FC in 2013/14.
• Gastón Pereiro (Uruguay) and Ángel Correa (Argentina) were on opposing sides in the 2015 South American Youth Championship final. Pereiro opened the scoring for Uruguay, but Correa scored the winner in Argentina's 2-1 victory.
• Guardado and Jeffrey Bruma are a booking away from a ban. Luuk de Jong serves a one-game suspension.
• PSV's record since matchday six is: W9 D1 L1.
• The Dutch champions have won their last eight Eredivisie fixtures.
• PSV lost 3-1 at home to FC Utrecht in the Dutch Cup quarter-finals on 4 February, a result that ended their 17-game unbeaten run.
• Three days later, January signing Marco van Ginkel scored his first goal for PSV as they gained revenge against Utrecht, winning 2-0 in the league. Van Ginkel was also on target in the 3-0 triumph over NEC Nijmegen on 14 February.
• On 14 January, Cocu extended his contract until the summer of 2019.
• Guardado has not played since he sustained a hamstring injury against De Graafschap on 30 January.
UEFA Champions League squad changes
• In: Aleksandar Boljević, Luiz Humberto Da Silva (Club Sporting Cristal), Marco van Ginkel (Chelsea FC, loan)
• Out: Moussa Sanoh, Rai Vloet (SC Cambuur, loan)
• Óliver Torres is a booking away from a suspension.
• Atletico's record since matchday six reads: W9 D4 L3.
• Having drawn 0-0 in Galicia, the Rojiblancos lost 3-2 to RC Celta de Vigo on 27 January in the second leg of their Copa del Rey quarter-final.
• After a wait of over four months, Fernando Torres finally moved from 99 to 100 goals for Atlético when he scored in the 3-1 Liga win against SD Eibar on 6 February.
• The former Liverpool FC and Chelsea FC forward was on target again the following week, scoring the only goal of the victory at Getafe CF.
• Yannick Carrasco sprained the external lateral ligament in his right ankle against Getafe.
• Jan Oblak extended his contract until summer 2021 on 9 February.
• Augusto Fernández (out since 30 January, left knee) and Tiago (28 November, right tibia fracture) are definitely out.
• Diego Godín (knee) and Stefan Savić (muscle problem) had been injured before returning for Sunday's 0-0 draw against Villarreal CF.