Cristiano Ronaldo missed a penalty as Real Madrid and city rivals Atlético slipped further behind Barcelona, who won again along with fellow last-16 hopefuls Bayern München and Paris.
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Málaga 1-1 Real Madrid (Albentosa 66; Ronaldo 33)
Cristiano Ronaldo missed a first-half penalty as Real Madrid – without injured forwards Karim Benzema and Gareth Bale – were held to a costly draw. Ronaldo nodded the visitors in front with his 22nd goal in 25 league outings before earning a spot kick and the chance to double his tally three minutes later. However, Carlos Kameni dived low to his left to keep out his effort. Instead, the visitors were forced to settle for a point, as Raúl Albentosa was left unmarked to equalise after the break. Zinédine Zidane's charges now trail Liga leaders Barcelona by nine points with 13 games remaining.
Atlético Madrid0-0 Villarreal
A point and a place higher than their city neighbours, Atlético were also frustrated on Sunday, being held to just their second goalless draw in the Liga this term. Antoine Griezmann headed narrowly wide in a tight first half before Alphonse Aréola came to Villarreal's rescue after the break to deny Ángel Correa, the visitors keeping a fifth consecutive clean sheet in all competitions.
Roma 5-0 Palermo (Džeko 30 89, Keita 52, Salah 60 62)
Luciano Spalletti's charges bounced back from their Madrid loss with a fifth straight Serie A success, thanks in large part to Edin Džeko and Mohamed Salah. Džeko's two goals brought him his first double since he joined the Giallorossi last summer, while former Fiorentina winger Salah enjoyed his first brace in Serie A. Saydou Keita was also on target as Roma consolidated their hold on fourth spot.
Chelsea 5-1 Manchester City (Costa 35, Willian 48, Cahill 53, Hazard 67, Traoré 89; Faupala 37)
Chelsea eased into the FA Cup quarter-finals with a comforable win against a much-changed City side. Ahead of Wednesday's last-16 tie at Dynamo Kyiv, Manuel Pellegrini rested a number of regulars and handed five academy players – Tosin Adarabioyo, Bersant Celina, Aleix García, Manuel Garcia and David Faupala – their full debuts. Diego Costa headed in Eden Hazard's cross to break the deadlock before Faupala gave City hope 94 seconds later, but the Blues made their experience count as Willian, Gary Cahill, Hazard and substitute Bertrand Traoré all struck.
Oostende 5-2Gent(Jonckheere 12 55, A.Milić 15, Musona 36, El Ghanassy 90+1; Kums 7pen, Depoitre 41)
Having conceded three at home to Wolfsburg in midweek, Hein Vanhaezebrouck's charges shipped five in West Flanders as they fell to a fourth reverse in five outings in all competitions. Sven Kums had given the Buffalos a seventh-minute lead via a spot kick; however, the hosts scored three without reply before Laurent Depoitre reduced the deficit late in the first half. The visitors conceded another ten minutes after the restart, then lost Nana Asare to a second bookable offence. Oostende sealed an emphatic home triumph in added time to leave Gent three points adrift in Belgium.
Arsenal 0-0 Hull City
The Gunners will travel to Humberside for a replay of their FA Cup fifth round tie after neither side could find the winner in north London. A Joel Campbell free-kick turned onto the post by goalkeeper Eldin Jakupović was the closest either team came, as the Tigers ended a 14-game winning run in the competition for Arsenal, who have lifted the trophy for the past two seasons.
Las Palmas 1-2 Barcelona (Willian José 10; Suárez 6, Neymar 39)
It is eight Liga wins on the bounce for the Blaugrana, Luis Suárez opening the scoring with his 25th goal in 24 league games this season. The early lead lasted just four minutes before Neymar restored the advantage prior to half-time, leaving Luis Enrique's side eight points clear after their Madrid rivals both dropped points. The Azulgrana are now 32 games without defeat in all competitions.
Bayern München 3- 1 Darmstadt (Müller 49 71, Lewandowski 84; Wagner 26)
Bayern conceded in the first half of a Bundesliga match for the first time since November but managed to come from behind at the interval to see off the visitors. Thomas Müller, with two, and Robert Lewandowski both found the target to take their combined tally to 39 in the Bundesliga, the most ever by a strike partnership after 22 games of a German league season.
Paços Ferreira 1-3 Benfica (Diego Jota 23; Mitroglou 13, Jonas 45+2, Lindelöf 57)
Both members of the Eagles' deadly strike force were on target as Benfica drew level on points with Sporting CP at the summit for at least a couple of nights ahead of the Lions' meeting with Boavista on Monday. Kostas Mitroglou opened the scoring with his 13th of the league campaign and Jonas restored the advantage in first-half added time, notching his 23rd in just 24 games. Victor Lindelöf added the third.
Paris 4-1 Reims (Van der Wiel 12, Ibrahimović 43 68, Cavani 45+1; Oniangué 34)
Paris Saint-Germain continue to dominate all comers in Ligue 1, beating Reims 4-1 to make it 22 wins in their last 24 fixtures in all competitions. Zlatan Ibrahimović's two goals took his tally to 23 in 21 league games this season. Laurent Blanc's side remain 24 points clear at the top of the table and have still lost only once in all competitions this season.
PSV Eindhoven 2-0 Heracles (Pröpper 3, Pereiro 45pen)
PSV refused to give rivals Ajax the chance to usurp them at the top of the Eredivisie this weekend, with a professional success against fourth-placed Heracles. Davy Pröpper's calm outside-of-the-foot finish put the hosts into an early lead and Gastón Pereiro rubber-stamped the victory seconds before the interval to ensure an eighth successive league win.
Hertha 1-1 Wolfsburg (Kalou 60; Schäfer 53)
Dieter Hecking's charges remain eighth in the Bundesliga after being held in the capital. The Wolves, who have won their last three UEFA Champions League fixtures, have picked up just one victory in their last nine games in the German top flight. Marcel Schäfer gave them a 53rd-minute lead at Hertha, but the hosts, up to third, equalised on the hour through Salomon Kalou.
Bologna 0-0 Juventus
Juventus failed to make it 16 consecutive Serie A victories. Patrice Evra headed wide from a corner with the best chance of the first half while Paul Pogba fired off target twice after the break as the visitors dominated but could not find the net.
No game: Dynamo Kyiv and Zenit
All times CET.