Victory against Lyon would take Juventus into the round of 16 and could end the Ligue 1 side's hopes, but visiting coach Bruno Génésio plans a positive approach in Turin.
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- Juventus will book a last-16 place with a win; Lyon out if Sevilla win the other game
- The Bianconeri are on an 18-match unbeaten home run in Europe
- Forwards Dybala and Pjaca ruled out for the hosts, Lemina suspended
- Moise Kean could be first 2000-born player in UEFA Champions League
- Juventus won 1-0 in France when these sides met a fortnight ago
Juventus: Buffon; Barzagli, Bonucci, Benatia; Dani Alves, Pjanić, Marchisio, Khedira, Alex Sandro; Mandžukić, Higuaín.
Out: Lemina (suspended), Chiellini (thigh), Dybala (out), Pjaca (calf)
Lyon: Lopes; Mammana, Nkoulou, Diakhaby; Rafael, Darder, Gonalons, Tolisso, Rybus; Fekir, Lacazette.
Out: Jallet (back) Valbuena (shoulder)
Misses next match if booked: Rafael
Massimiliano Allegri, Juventus coach
Lyon played well against us and had a good away win at the weekend but we cannot waste what we did in Lyon two weeks ago. We respect Lyon because they are a very good team, with two dangerous forwards who can trouble any side. We are doing well but we can obviously improve.
Marchisio will certainly play tomorrow. He gives us experience and quality, and has improved a lot in recent years as a deep-lying playmaker. Khedira will also play, but don't ask me who the third midfielder will be because I'm not going to tell you.
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Bruno Génésio, Lyon coach
The victory in Toulouse was very important for us because we had to reverse a bad trend. It was a good injection of confidence, which we needed ahead of a tough game like this. We will have to be very careful with the ball because we cannot afford to allow Juve to have too much possession. We need a victory so we have to use our attackers – we will see which system suits us best in this sense.
Obviously there is a certain difference in terms of experience but we must prove that we can compete with a strong team like Juve. [Gianluigi] Buffon? We have great respect for the player and the man. His mentality is just incredible. [Alexandre] Lacazette is proving to be a great striker in Ligue 1 and I'm sure he can prove his worth in Europe as well.
Juventus 2-1 Napoli (Bonucci 50, Higuaín 70; Callejón 54)
José Callejón sped in to get his seventh Serie A goal this term, but the Partenopei were denied a point by their former hero, Gonzalo Higuaín pointedly refusing to celebrate after scoring the winner against his old club.
Toulouse 1-2 Lyon(Jullien 26; Lacazette 15p 52)
Alexandre Lacazette leapfrogged Juninho Pernamubacano to go fourth in OL's all-time scoring chart after taking his tally to 101 in Toulouse. Lyon thus ended a run of three straight losses in all competitions despite Rafael's dismissal.
Form guide (all competitions, most recent first)
Reporter's view: Paolo Menicucci (@UEFAcomPaoloM)
Juventus are missing Paulo Dybala's creativity while Mario Mandžukić and Higuaín are probably too similar to ever become the perfect attacking pair. However, the Italian champions remain favourites at home where they have won their last 22 games in Serie A. Lacazette and company proved they can trouble the Juve defence two weeks ago, when only Gianluigi Buffon's brilliance saved the Bianconeri, and the hosts will know the potential danger of leaving too much space for Lyon's pacy forwards.
Did you know?
Juventus have never lost at home to French opponents, winning ten and drawing two. For more nuggets of information, check out our match background.