Having comfortably won their last three games against Shakhtar, a repeat would guarantee Manchester City's last-16 place.
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Manchester City's winning run in this season's UEFA Champions League was ended on Matchday 4, but Josep Guardiola's side are nevertheless within touching distance of the last 16 as they welcome a Shakhtar Donetsk side who suffered a chastening defeat on their last visit to Manchester.
• This is the third successive season in which the teams have been drawn together in the UEFA Champions League group stage, with City enjoying much the better of the previous encounters – including a 3-0 win in Kharkiv on Matchday 1 this season thanks to goals from Riyad Mahrez, İlkay Gündoğan and Gabriel Jesus.
• City have ten points, five more than both Shakhtar and Dinamo Zagreb with Atalanta on one. The English club will therefore be through if they avoid defeat against Shakhtar or if Dinamo do not beat Atalanta in Group C's other Matchday 5 fixture. City will be confirmed in first place if they win, or if they draw and Dinamo do not win.
• Shakhtar will qualify with a win if Dinamo lose to Atalanta, due to Shakhtar's head-to-head away goals superiority over Dinamo.
• Matchday 1 made it four wins in five matches against Shakhtar for City, who have scored 12 goals without conceding in the last three games between the clubs.
• David Silva, Aymeric Laporte and Bernardo Silva got City's goals at the Metalist Stadium in Kharkiv on 23 October 2018, ending Shakhtar's seven-game unbeaten record at home to English clubs (W5 D2).
• David Silva also opened the scoring in City's 6-0 home win on Matchday 4 last season, Jesus contributing a hat-trick that included two penalties and Raheem Sterling and Mahrez completing the scoring. City went through to the round of 16 as group winners, while Shakhtar finished third in the section.
• The teams were paired together for the first time in the 2017/18 group stage, when home sides held the upper hand. City were 2-0 winners in Manchester on Matchday 2, second-half goals from Kevin De Bruyne and Sterling securing the points.
• Guardiola's side travelled to Ukraine for their final fixture with a place in the round of 16 already assured, but looking to make it six wins out of six in the section. Instead Shakhtar secured their own place in the knockout stages with a 2-1 victory, goals from Bernard and Ismaily proving enough despite Sergio Agüero's added-time penalty.
• City followed up their opening win at at Shakhtar with home victories against Dinamo (2-0) and Atalanta (5-1), the latter then ending their four-game winning streak in the UEFA Champions League with a 1-1 draw in Italy. City have scored 25 goals in their last eight UEFA Champions League matches; since losing at home to Lyon on Matchday 1 last season (1-2) their record is W10 D2 L1 with 40 goals scored and 12 conceded.
• In 2018/19, City recovered from that defeat at home to Lyon to finish first in Group F ahead of the French club, Shakhtar and Hoffenheim, picking up 13 points. They brushed aside Schalke 10-2 on aggregate in the last 16, but for the second year running lost to English opposition in the quarter-finals, Tottenham eliminating them on away goals after a dramatic 4-4 aggregate draw (0-1 a, 4-3 h).
• Guardiola's side have won 11 of their last 19 European matches, home and away, losing six. They have won their last six home games, scoring 26 goals and conceding five.
• City have won three of their four home matches against Ukrainian visitors without conceding, the exception a 0-0 draw against Dynamo Kyiv in the 2015/16 UEFA Champions League round of 16 second leg (3-1 aggregate). No Ukrainian side has therefore found the net at the City of Manchester Stadium.
• This is the Citizens' ninth UEFA Champions League campaign; they have been involved in the group stage every season since 2011/12 and have reached the round of 16 or better in the last six campaigns.
• The 6-0 defeat of Shakhtar last season was City's record win in UEFA competition; they quickly surpassed that with a 7-0 defeat of Schalke in the round of 16 second leg. They scored 20 goals in their five home games in 2018/19.
• City's best UEFA Champions League performance was reaching the 2015/16 semi-finals.
• Champions of England for the second season running and sixth overall – four of those titles having come in the last eight years – City also lifted the FA Cup and League Cup in 2018/19, becoming the first English club to win all three domestic trophies in one season.
• Shakhtar have mounted stirring comebacks in both away games so far. On Matchday 2 they came from behind to win 2-1 at Atalanta, substitute Manor Solomon scoring the decisive goal five minutes into added time. They then scored twice in added time, through Júnior Moraes and a Tetê penalty, to salvage a 3-3 draw at Dinamo Zagreb in their most recent fixture having been held 2-2 at home by the Croatian club.
• Shakhtar have won only two of their last 11 UEFA Champions League matches (D5 L4).
• The Donetsk club picked up four points away from home in last season's group stage; the win at Atalanta was only their third in their last 14 away UEFA Champions League matches, group stage to final (D3 L8).
• Quarter-finalists in 2010/11, Shakhtar won only one of their six matches in last season's group stage, collecting six points to finish behind City and Lyon in Group F. They then went down 6-3 on aggregate to Eintracht Frankfurt in the UEFA Europa League round of 32 (2-2 h, 1-4 a).
• Shakhtar have got out of their UEFA Champions League group in three of their last six participations.
• The Pitmen have lost on seven of their eight trips to England, avoiding defeat only on their second visit, a 1-1 draw at Tottenham in a round of 32 second leg during their victorious UEFA Cup campaign of 2008/09 (3-1 aggregate). In those seven defeats, Shakhtar scored six goals and conceded 22.
• Shakhtar qualified as winners of the Ukrainian league, claiming the title for the 12th time in 2018/19, when they completed a domestic double for the third season in succession.
Links and trivia
• Shakhtar's record European defeat was a 7-0 loss at Guardiola's Bayern München in the 2014/15 round of 16. The Pitmen lost four of their five fixtures against Barcelona when Guardiola was in charge, including the 2009 UEFA Super Cup (0-1); their 12 games against clubs coached by the Spaniard make him their most frequent opponent in European competition.
• Fernandinho was a Shakhtar player between 2005 and 2013 when he left for City, scoring 31 goals in 183 league outings. He was named Ukraine's Premier League player of the year in 2007/08, and amassed six league titles, four Ukrainian Cups and the 2008/09 UEFA Cup.
• Fernandinho's Shakhtar team-mates included Andriy Pyatov, Serhiy Kryvtsov, Taras Stepanenko, Taison, Alan Patrick and Dentinho.
• Oleksandr Zinchenko was initially a Shakhtar trainee, but left the club in 2014 without making a senior appearance. He signed for City in July 2016 following a spell with Russian side Ufa.
• Yevhen Konoplyanka scored in Sevilla's 2-1 defeat at City of Manchester Stadium in the 2015/16 UEFA Champions League group stage.
• Konoplyanka was also on target against England at Wembley in a 1-1 2014 FIFA World Cup qualifying draw. Sterling and Kyle Walker were unused substitutes.
• International team-mates:
Fernandinho, Ederson, Gabriel Jesus & Taison, Ismaily (Brazil)
Oleksandr Zinchenko & Andriy Pyatov, Serhiy Kryvtsov, Taras Stepanenko, Viktor Kovalenko, Marlos, Bohdan Butko, Mykola Matviyenko, Yevhen Konoplyanka, Serhiy Bolbat, Júnior Moraes (Ukraine)
• Bernardo Silva made his 50th appearance in UEFA club competition on Matchday 4.
• Claudio Bravo is, at 36 years 207 days, the oldest player to have appeared in this season's UEFA Champions League – though his substitute appearance against Atalanta on Matchday 4 ended prematurely as he was sent off.
• City had won ten of 11 matches in all competitions, including five in a row since a 2-0 defeat at home to Wolverhampton Wanderers on 6 October, before Matchday 4; four days after being held at Atalanta, City were beaten 3-1 away to Premier League leaders Liverpool.
• That was City's third defeat in this season's Premier League, one fewer than they suffered in the whole of 2018/19.
• City have still suffered only three defeats in their last 28 matches in all competitions (W22 D3).
• City came from a goal down to beat Chelsea 2-1 at home on Saturday evening, Riyad Mahrez getting the winner in the first half.
• Kevin De Bruyne, who scored City's first goal on Saturday, has provided nine assists in this season's Premier League – the most in the division.
• English League Cup winners in the last two seasons, and four of the last six campaigns, City reached this season's quarter-finals with a 3-1 home win against Southampton on 29 October. They will visit third division Oxford in the last eight on 18 December.
• City were 8-0 winners at home to Watford in the Premier League on 21 September, their biggest win in the English top flight. They led 5-0 after 18 minutes, the fastest any side has established that scoreline in a Premier League match.
• Sergio Agüero found the net in City's first six league games of the season, eight goals in all, but has scored only once in seven matches since. He was taken off after 77 minutes on Saturday with a suspected groin injury.
• Josep Guardiola's side have scored 55 goals in their 20 matches this season, and 37 in their 13 league games.
• Raheem Sterling has scored 14 goals in 18 club games this season, and has 18 goals and nine assists in 23 games for City and England in 2019/20.
• Bernardo Silva set up a goal as Portugal qualified for UEFA EURO 2020 with a 2-0 win in Luxembourg on 17 November; he had provided a goal and an assist in the 6-0 home win against Lithuania three days earlier.
• John Stones was recalled to the England side for the 7-0 win against Montenegro at Wembley that secured their UEFA EURO 2020 qualification.
• De Bruyne provided two assists as Belgium won their European Qualifier 4-1 in Russia on 16 November and scored twice himself, adding another assist, in the 6-1 home win against Cyprus three days later.
• Agüero scored in Argentina's 2-2 friendly draw against Uruguay on 18 November.
• On 15 November Phil Foden scored in England's 3-0 win in Albania in qualifying for the 2021 UEFA European Under-21 Championship.
• Ederson missed the defeat at Liverpool having been withdrawn at half-time at Atalanta on 6 November with a muscular injury; he returned on Saturday.
• Oleksandr Zinchenko has not played since 14 October and subsequently underwent knee surgery.
• Aymeric Laporte damaged the cartilage and lateral meniscus in his right knee during a 4-0 home win against Brighton on 31 August and is expected to be sidelined for around six months.
• Leroy Sané is also facing a lengthy spell on the sidelines after suffering an anterior cruciate ligament injury to his right knee during the FA Community Shield against Liverpool on 4 August.
• City won the Community Shield for the sixth time overall – and second year in a row – with a 5-4 shoot-out defeat of Liverpool at Wembley, Sterling scoring City's goal in a 1-1 draw.
• Shakhtar opened this season with a 2-1 Ukrainian Super Cup loss to Dynamo Kyiv, their third defeat in four years in the competition against their great rivals.
• That was Shakhtar's only domestic defeat this season until 30 October when they lost to the same opponents by the same scoreline after extra time in the Ukrainian Cup round of 16.
• Shakhtar's perfect start to the league season, in which they had scored 36 goals scored and conceded six, was ended by a goalless draw at home to Olexandriya on 27 October.
• The Donetsk club had previously won all 11 league games this season, and were on a 13-match winning run in the competition overall stretching back to 2018/19.
• On 10 November, Shakhtar won 1-0 at home against Dynamo Kyiv. Shakhtar are now unbeaten in 44 league games (W38 D6), since a 1-0 away loss to Dynamo on 3 August 2018. They were 4-1 winners at home to Lviv on Friday.
• Júnior Moraes scored a hat-trick against Lviv, making it 16 goals and six assists in Shakhtar's 21 competitive matches this season.
• Moraes (ankle) and Marlos (groin) missed Ukraine's recent internationals, as did Israel's Manor Solomon (hamstring); only Moraes recovered to face Lviv on Friday.
• Andriy Pyatov, Mykola Matviyenko, Serhiy Kryvtsov and Viktor Kovalenko helped Ukraine to finish their UEFA EURO 2020 qualifying campaign unbeaten with a 2-2 draw in Serbia on 17 November.