Possible line-ups and team news for Wednesday

Real Madrid v Sporting CP
Real Madrid: Casilla; Carvajal, Pepe, Ramos, Marcelo; Kroos, Casemiro, Modrić; Bale, Benzema, Ronaldo.
Out: Navas (heel), Coentrão (thigh)
Doubtful: none

Sporting: Patrício; João Pereira, Coates, Semedo, Zeegelaar; William Carvalho, Adrien, Ruiz; Campbell, Gelson, Dost.
Out: none
Doubtful: none

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Gonzalo Higuaín has been in fine form for Juventus this season©AFP/Getty Images

Juventus v Sevilla
Juventus: Buffon; Barzagli, Bonucci, Chiellini; Dani Alves, Khedira, Lemina, Pjanić, Evra; Higuaín, Dybala.
Out: Marchisio (knee), Sturaro (knee)
Doubtful: none

Sevilla: Rico; Mercado, Rami, Pareja; Iborra, N'Zonzi, Sarabia; Mariano, Vitolo, Kiyotake; Vietto.
Out: Nasri (ill), Kolodziejczak (suspended), Trémoulinas (knee)
Doubtful: none

Leverkusen v CSKA Moskva
Leverkusen: Leno; Jedvaj, Tah, Toprak, Wendell; Bender, Kampl; Brandt, Mehmedi; Pohjanpalo, Hernández.
Out: Bellarabi (groin), Yurchenko (calf)
Doubtful: Kruse (illness)

CSKA: Akinfeev; Mário Fernandes, V Berezutski, Ignashevich, Schennikov; Ionov, Wernbloom, Dzagoev, Eremenko, Golovin; Traoré.
Out: Cauņa (ankle)
Doubtful: none

Tottenham v Monaco
Tottenham: Lloris; Walker, Alderweireld, Vertonghen, Davies; Dier, Wanyama; Lamela, Alli, Eriksen; Kane.
Out: Rose (hamstring)
Doubtful: none

Tottenham are back in the UEFA Champions League©Getty Images

Monaco: Subašić; Raggi, Glik, Jemerson, Sidibé; Dirar, Fabinho, Moutinho, Traoré; Silva, Germain.
Out: Mendy (thigh), Mbappé (concussion)
Doubtful: Subašić (thigh)

Legia v Dortmund
Legia: Malarz; Broź, Dąbrowski, Rzeźniczak, Bereszyński; Langil, Moulin, Odjidja, Jodłowiec, Guilherme; Nikolić.
Out: Hloušek (suspended)
Doubtful: Pazdan (muscle problems), Kucharczyk (foot)

Dortmund: Bürki; Piszczek, Sokratis, Bartra, Schmelzer; Rode, Weigl, Castro; Dembele, Aubameyang, Schürrle.
Out: none
Doubtful: none

Club Brugge v Leicester
Club Brugge: Butelle; Van Rhijn, Engels, Denswil, De Bock; Vormer, Simons; Vanaken, Claudemir, Izquierdo; Diaby.
Out: Refaelov (pelvis), Wesley (ankle)
Doubtful: none

Jamie Vardy will lead the line for debutants Leicester©AFP/Getty Images

Leicester: Schmeichel; Hernández, Huth, Morgan, Fuchs; Mahrez, Drinkwater, Amartey, Albrighton; Okazaki, Vardy.
Out: Schlupp (muscle strain)
Doubtful: Simpson (hamstring), Mendy (ankle)

Porto v København
Porto: Casillas; Layún, Felipe, Marcano, Alex Telles; Danilo, Óliver Torres, André André, Otávio; André Silva, Depoitre.
Out: Maxi Pereira (ankle)
Doubtful: none

København: Olsen; Ankersen, Jørgensen, Johansson, Augustinsson; Verbič, Kvist, Delaney, Toutouh; Santander, Pavlović.
Out: none
Doubtful: none

Lyon v Dinamo Zagreb
Lyon: Lopes; Nkoulou, Yanga-Mbiwa, Morel; Rafael, Ferri, Gonalons, Darder, Rybus; Tolisso; Cornet.
Out: Kalulu (suspended), Lacazette (hamstring), Fekir (knee), Valbuena (groin), Grenier (fractured leg), Jallet (back)
Doubtful: none

Dinamo: Šemper; Stojanovič, Sigali, Schildenfeld, Pivarić; Machado, Jonas; Soudani, Ćorić, Fernandes; Henriquez.
Out: Antolić (knee), Mățel (groin)
Doubtful: none