Shakhtar Donetsk have a three-point cushion in second place in Group F and know inflicting a fourth defeat on bottom side Feyenoord would be a significant step towards the last 16.
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FC Shakhtar Donetsk will be looking to build on their valuable away win at Feyenoord when they welcome the Dutch champions to Ukraine.
• Shakhtar moved three points clear in second place in Group F with a 2-1 success in Rotterdam on matchday three that left their opponents bottom of the section without a point.
• Feyenoord will therefore be unable to finish in the top two if they do not win in Ukraine, where they have never been victorious in four previous visits.
• This is Shakhtar's sixth game against a club from the Netherlands – they lost all the first four, scoring three goals and conceding ten, before winning at Feyenoord.
• In the same competition in 1999/2000, Shakhtar were beaten 2-0 at Roda JC and 3-1 at home in the first round (1-5 aggregate).
• Shakhtar started 2017/18 with a 2-1 win at home to SSC Napoli on matchday one. The Donetsk team – who are playing their UEFA Champions League home games in Kharkiv this season, due to the political situation in Ukraine – have won only four of their last 13 home fixtures in the competition, group stage to final.
• Márcio Azevedo, Taison and Marlos all called the OSK Metalist Stadium home before joining Shakhtar from FC Metalist Kharkiv.
• Shakhtar are making their seventh group stage appearance in eight seasons and their 12th in total – all since 2000. They have got to the last 16 on three occasions: 2010/11 (when they reached the quarter-finals), 2012/13 and 2014/15.
• In 2016/17, the Ukrainian side lost to BSC Young Boys in the third qualifying round (2-0 home, 0-2 away, 2-4 on penalties). They eventually made it to the UEFA Europa League round of 32, going down to RC Celta de Vigo (1-0 away, 0-2 home aet).
• That Celta defeat ended Shakhtar's five-game winning run, and a nine-match unbeaten streak, at home in Europe.
• Feyenoord lost 3-1 at Napoli in their second fixture, making the 3-0 victory at R. Standard de Liège in the UEFA Europa League group stage on 12 December 2014 the only win in their last 15 European away games (D3 L12).
• Feyenoord's last away victory in the UEFA Champions League, group stage to final, was the 1-0 triumph at Newcastle United FC on 24 September 2002.
• The Dutch side's away record against clubs from Ukraine is W0 D2 L2. Their most recent fixtures came in the 2016/17 UEFA Europa League group stage, where they won 1-0 at home to FC Zoryn Luhansk before a 1-1 away draw in Odessa.
• After beating Zorya 4-3 at home in the 2014/15 UEFA Europa League play-offs following a 1-1 away draw, Feyenoord were unbeaten in four matches (W2 D2) against Ukrainian opposition, since a 1-0 home loss to FC Dynamo Kyiv in August 2012. That last result had been the third defeat in their first four games against teams from Ukraine, the other drawn.
• Having lifted a first Eredivisie title in 18 years last season, Feyenoord are in the last 32 of the UEFA Champions League for the first time since 2002/03, when they were eliminated in the first group stage.
• The Rotterdammers lost in the third qualifying round in both 2012/13 (to Dynamo Kyiv) and 2014/15 (to Beşiktaş JK).
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• Giovanni van Bronckhorst was in the Netherlands side that recorded a 3-0 friendly win against Ukraine at the Stadion Feijenoord on 24 May 2008.
• Andriy Pyatov and Kenneth Vermeer faced each other twice at the 2006 UEFA Under-21 Championship in Portugal. Ukraine beat Netherlands 2-1 in the group stage but were defeated 3-0 in the final.
• Yaroslav Rakitskiy serves a one-game suspension after being sent off on matchday three.
• Shakhtar are unbeaten in 13 domestic matches, winning ten. They have won 12 and drawn three of their last 15 games in all competitions.
• Shakhtar had won their last six home games in all competitions before Saturday's 1-1 league draw with FC Stal Kamianske.
• Before Saturday Shakhtar had not scored just once in a game this season: they have hit two eight times, three on four occasions and four twice. Paulo Fonseca's side have drawn four blanks.
• Shakhtar reached a 12th straight Ukrainian Cup quarter-final with a thrilling 4-3 victory after extra time at Zorya.
• Facundo Ferreyra struck twice, including a 90th-minute equaliser, with substitutes Viktor Kovalenko and Gustavo Blanco Leschuk also on target, the latter scoring the winner in the 117th minute.
• Marlos and Bernard missed the game against Zorya while David Khocholava made only his second start of the season.
• Karim El Ahmadi is one booking away from a ban.
• Feyenoord have lost six of their last 11 matches in all competitions, with two of their three victories in that spell coming via the Dutch Cup.
• Feyenoord have missed their last four penalties.
• Feyenoord suffered a 4-1 home defeat against AFC Ajax on 22 October. Jens Toornstra scored for the first time since August while Nicolai Jørgensen missed a penalty.
• AVV Swift were dispatched 4-1 on 25 October as Feyenoord qualified for the Dutch Cup round of 16.
• Sam Larsson scored the first hat-trick of his professional career in that game while Michiel Kramer, who earlier missed a penalty, also was on target.
• Goalkeeper Kenneth Vermeer started for the first time this season following a hand injury while 17-year-old defender Lutsharel Geertruida made his debut against Swift.
• Feyenoord were held 1-1 at lowly Roda JC on Saturday despite Steven Berghiuis scoring his ninth goal of the season.