Contenders at the top of the Premier League in recent years, Tottenham and Manchester City now meet in Europe for the first time.
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Tottenham Hotspur and Manchester City have been contenders at the top of the Premier League in recent years and now translate their rivalry to the European stage for the first time.
• This is Tottenham's first European game in their new stadium; their first four home UEFA Champions League games this season were played at Wembley.
• While Spurs are in the UEFA Champions League quarter-finals for the first time since their sole previous appearance eight years ago, this is City's third last-eight tie in the past four seasons – and a second successive contest at this stage against a fellow English club.
• Both come into this match buoyed by positive round of 16 performances against German opponents, Spurs seeing off Borussia Dortmund 4-0 on aggregate while City recorded their biggest European victory last time out, dismantling Schalke 7-0 in Manchester to complete a 10-2 success over the two legs.
• There has been very little between Tottenham and City in domestic football over the years. In 156 competitive meetings, City have won 61 to Spurs' 60, with 35 draws – although City have won the last three fixtures between the sides.
• In this season's Premier League, a sixth-minute Riyad Mahrez goal proved enough for City to pick up three points against Spurs at Wembley on 29 October. The league game at the City of Manchester Stadium is scheduled for 20 April – three days after the second leg of this tie.
• In English domestic knockout football, Spurs have won nine of the teams' 14 ties – including five of the last six.
• Tottenham have won one and lost one of their previous two European Cup quarter-finals:
2010/11 Real Madrid L 0-5 (0-4 a, 0-1 h)
1961/62 Dukla Praha W 4-2 (0-1 a, 4-1 h)
• This is Spurs' fourth all-English European tie, but a first in 46 years, since an away-goals defeat by Liverpool in the 1972/73 UEFA Cup semi-final (0-1 a, 2-1 h). That made Spurs' two-legged record against English clubs W1 L2.
• Tottenham did win a European trophy at the expense of domestic opponents, overcoming Wolverhampton Wanderers 3-2 on aggregate (2-1 away, 1-1 home) in the first UEFA Cup final in 1972.
• Before beating Dortmund 3-0 in the round of 16 first leg Tottenham had never won a home match in the UEFA Champions League knockout rounds (D1 L2), scoring just one goal in those first three fixtures.
• This season, Mauricio Pochettino's side lost 4-2 at home to Barcelona in their first home game, but beat PSV Eindhoven (2-1) and Internazionale (1-0) in the next two. That helped them overtake Inter to snatch second place in Group B behind Barça; Spurs had just one point after three matches.
• The London club also won three of their four home games in last season's UEFA Champions League. Before beating Dortmund on matchday one in 2017/18, they had won just one of their previous five European home fixtures.
• City's record in European Cup quarter-finals is W1 L1:
2017/18 Liverpool L 1-5 (0-3 a, 1-2 h)
2015/16 Paris Saint-Germain W 3-2 (2-2 a, 1-0 h)
• City have played four previous games against English clubs in European competition, and lost them all. Indeed, Gabriel Jesus's early goal in the quarter-final second leg against Liverpool 12 months ago is the only one they have managed in those four fixtures, with seven conceded.
• In addition to last season's defeat by Liverpool, City were also beaten by eventual winners Chelsea in the 1970/71 European Cup Winners' Cup semi-finals, losing 1-0 both away and at home.
• City's best UEFA Champions League performance was reaching the 2015/16 semi-finals.
• The winners of Group F in the autumn, Manchester City are in the knockout stages for the sixth year in a row, although this is only the third time they have made it to the last eight.
• City have twice recorded their biggest European victory in this season's UEFA Champions League, beating Shakhtar Donetsk 6-0 in Manchester on matchday four before the 7-0 defeat of Schalke last time out.
• Josep Guardiola's side have won seven of their last 13 European matches, home and away – losing five. Away from home it is four wins in six matches (D1 L1), the sole defeat coming in England.
• City have scored two or more goals in each of their four away games in this season's competition (W3 D1).
Links and trivia
• City manager Guardiola has lost just two of his 14 managerial contests with Mauricio Pochettino (W8 D4); the pair also crossed paths as coaches in Spain with Barcelona and Espanyol respectively.
• Kyle Walker was a Tottenham player between 2011 and signing for City in 2017, scoring four goals in 183 Premier League appearances for the Lilywhites.
• Kieran Trippier joined City's academy aged nine and stayed until 2012, when he departed for Burnley on a permanent deal having failed to make a first-team appearance.
• International team-mates:
Eric Dier, Danny Rose, Kieran Trippier, Dele Alli, Harry Kane & John Stones, Kyle Walker, Fabian Delph, Raheem Sterling (England)
Toby Alderweireld, Jan Vertonghen & Vincent Kompany, Kevin De Bruyne (Belgium)
Lucas Moura & Ederson, Danilo, Fernandinho, Gabriel Jesus (Brazil)
Paulo Gazzaniga, Juan Foyth, Erik Lamela & Nicolás Otamendi, Sergio Agüero (Argentina)
Hugo Lloris & Benjamin Mendy (France)
• Lloris and Mendy were both members of France's victorious 2018 FIFA World Cup squad.
• Heung-Min Son's next appearance in UEFA club competition will be his 50th.
• Tottenham's most recent game was a 2-0 Premier League win against Crystal Palace on 3 April – the first match at Spurs' new Tottenham Hotspur Stadium home. Son scored the first goal at the ground, Christian Eriksen supplying the second.
• That was only Spurs' second win in their last seven matches (D1 L4) – all those defeats coming away from home.
• Spurs have drawn only four of their 47 games in 2018/19 in all competitions (W29 L14).
• Mauricio Pochettino's side have kept four clean sheets in their last 15 fixtures.
• Serge Aurier has not played since suffering a hamstring injury in Ivory Coast's 3-0 Africa Cup of Nations qualifying win against Rwanda on 23 March.
• Eric Dier was forced off early in England's 5-0 UEFA EURO 2020 qualifying win against the Czech Republic on 22 March with a hip injury. Harry Winks recovered from a similar problem to come on as a substitute against Palace, his first appearance since 5 March.
• Erik Lamela, who has not played since the round of 16 second leg at Borussia Dortmund, has a hamstring injury.
• Aymeric Laporte made his 50th appearance in UEFA club competition in the round of 16 second leg.
• City are the top scorers in this season's UEFA Champions League with 26 goals.
• City have won 21 of their last 23 games in all competitions, losing one – they have scored 72 goals in that run, conceding only 11.
• The one game in that sequence that City drew was against Chelsea in the League Cup final at Wembley on 24 February; they went on to win 4-3 on penalties to lift the trophy for the sixth time overall and the fourth in the last six seasons.
• On Saturday City reached the FA Cup final for the first time since 2013 – and the 11th overall – with a 1-0 defeat of Brighton at Wembley, Gabriel Jesus scoring the only goal early on.
• The English champions have won their last eight league matches.
• City have won nine of their last ten away games in all competitions, and all of the last six.
• City have kept seven clean sheets in their last nine matches in all competitions.
• Josep Guardiola's side have scored five or more goals in ten of their 52 games this season.
• City's home record in all competitions this season is W23 L2 – they have won the last 11, scoring 48 goals and conceding three.
• The Manchester club beat third-tier Burton Albion 9-0 at home in the first leg of the League Cup semi-final on 9 January – City's biggest win since a 10-1 defeat of Huddersfield in 1987. They won the return leg 1-0.
• The Citizens signed 18-year-old midfielder Ante Palaversa from Hajduk Split in January, loaning the teenager back to the Croatian club for the rest of the season.
• Sergio Agüero, who has four goals in his last three matches and 15 in his last 14, suffered a muscle injury in a 2-0 win at Fulham on 30 March. The Argentinian missed the home win against Cardiff by the same scoreline four days later, a game in which Oleksandr Zinchenko went off midway through the first half with a hamstring problem; neither featured against Brighton.
• Kyle Walker was taken off at half-time on Saturday with a hamstring problem.
• Benjamin Mendy had surgery on the cartilage in his left knee on 14 November. Until he played 79 minutes against Brighton at the weekend his only appearance since then had been in the second leg at Burton on 23 January.
• Claudio Bravo has been out since sustaining an Achilles problem on 20 August.