Holders Sevilla FC were the only away side to win their round of 16 first leg, though their two-goal victory was matched by FC Zenit, VfL Wolfsburg and SSC Napoli.
Article top media content
The UEFA Europa League round of 16 ties are beginning to take shape following Thursday's first legs.
Click the links below for match reports, statistics, team lineups, photos and – until midnight CET on Friday – video highlights.
FC Zenit 2-0 Torino FC
VfL Wolfsburg 3-1 FC Internazionale Milano
Club Brugge KV 2-1 Beşiktaş JK
FC Dnipro Dnipropetrovsk 1-0 AFC Ajax
Everton FC 2-1 FC Dynamo Kyiv
ACF Fiorentina 1-1 AS Roma
Villarreal CF 1-3 Sevilla FC
SSC Napoli 3-1 FC Dinamo Moskva
Perhaps the standout moment of the night came at El Madrigal, where Sevilla midfielder Vitolo set a new record for the fastest ever UEFA Europa League goal, opening the scoring after just 13.21 seconds. It was also a good night for Belgium, with Axel Witsel on target for Zenit, Kevin De Bruyne scoring twice for VfL Wolfsburg and Club Brugge KV seeing off Beşiktaş JK.
The second legs take place next Thursday, 19 March. The draw for the quarter-finals will take place in Nyon the following day.